Bristol Myers, Nektar Melanoma Doublet Therapy Trial Fails To Show Clinical Benefit


27% profit every 20 days?

This is what Nic Chahine averages with his option buys. Not selling covered calls or spreads… BUYING options. Most traders don’t even have a winning percentage of 27% buying options. He has an 83% win rate. Here’s how he does it.


  • Bristol Myers Squibb Co (NYSE:BMY) and Nektar Therapeutics (NASDAQ:NKTR) have an update following the first analysis of the Phase 3 PIVOT IO-001 study of bempegaldesleukin combined with Opdivo (nivolumab) in previously untreated unresectable or metastatic melanoma patients.
  • The review by an independent Data Monitoring Committee (DMC) suggested that the study did not meet the primary endpoints of progression-free survival (PFS) and objective response rate (ORR).
  • The DMC notified the companies that the third primary endpoint of overall survival (OS) did not meet statistical significance.
  • The companies have decided to unblind the trial and perform no additional analyses for the OS endpoint. 
  • The companies have decided to discontinue enrollment and unblind the ongoing PIVOT-12 study in adjuvant melanoma, which evaluates bempegaldesleukin plus Opdivo compared to Opdivo in high-risk patients for recurrence after complete resection of melanoma. 
  • The other four studies ongoing for bempegaldesleukin plus Opdivo in renal cell carcinoma and bladder cancer are continuing, with initial results expected in 1H of 2022.
  • Price Action: NKTR shares are down 56.1% at $4.67, and BMY stock is up 1.34% at $69.80 during the market session on the last check Monday.

27% profit every 20 days?

This is what Nic Chahine averages with his option buys. Not selling covered calls or spreads… BUYING options. Most traders don’t even have a winning percentage of 27% buying options. He has an 83% win rate. Here’s how he does it.


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