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The FDA has signed off TScan Therapeutics Inc's (NASDAQ:TCRX) investigational new drug (IND) application for TSC-100 in hematologic malignancies patients undergoing allogeneic hematopoietic cell transplantation (HCT).
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- The target of TSC-100 is the minor histocompatibility antigen HA-1, which is a lineage-specific antigen found on blood cells.
- The Company will now submit the clinical protocol to Institutional Review Boards (IRB) for the initial study sites and expects to begin dosing patients in 1H of 2022.
- Preliminary data is expected in 2H of 2022.
- TScan plans to initiate a multi-arm Phase 1 umbrella trial designed to evaluate TSC-100 compared to standard-of-care in patients undergoing allogeneic HCT.
- The Company will then initiate the TSC-101 arm of this trial in the same patient population. Primary endpoints include safety and dose-finding.
- As of September 30, 2021, the Company held cash & cash equivalents of $182.9 million that is expected to fund its operating expenses into 2024.
- Price Action: TCRX shares are trading 6.05% lower at $4.33 during the market session on the last check Monday.
Crypto Whales Are Loading Up — Are You?
New research shows the biggest crypto buyers are back. And this time? They could hold for the possibility that Bitcoin will surpass $100,000 in 2024. You don’t want to miss the next massive crypto bull run like we saw in 2020 and 2021. To know exactly what’s going on and what to buy… Get Access To Benzinga’s Best Crypto Research and Investments For Only $1.