Cassava Sciences Kickstarts Second Late-Stage Alzheimer's Trial With Simufilam


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  • Cassava Sciences Inc (NASDAQ:SAVA) has initiated a second Phase 3 study of simufilam in patients with Alzheimer's disease. 
  • The second Phase 3 study is designed to evaluate the safety and efficacy of oral simufilam 100 mg and 50 mg over 78 weeks over 78 weeks in approximately 1,000 patients.
  • Cassava Sciences' is conducting the Phase 3 program in Alzheimer's under Special Protocol Assessments (SPA) from the FDA.
  • The first Phase 3 RETHINK-ALZ study is designed to evaluate the safety and efficacy of oral simufilam 100 mg in enhancing cognition and slowing cognitive and functional decline over 52 weeks. 
  • This study plans to enroll approximately 750 patients with mild-to-moderate Alzheimer's disease. 
  • The Company commenced patient screening for RETHINK-ALZ in October 2021, followed by patient dosing in November 2021.
  • Recently, SEC launched a probe into claims that Cassava Sciences' manipulated data key to its case for simufilam.
  • Price Action: SAVA shares are up 0.57% at $47.34 during the market session on the last check Thursday.

27% profits every 20 days?

This is what Nic Chahine averages with his options buys. Not selling covered calls or spreads... BUYING options. Most traders don't even have a winning percentage of 27% buying options. He has an 83% win rate. Here's how he does it.


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Posted In: BiotechNewsHealth CareSmall CapMoversTrading IdeasGeneralAlzheimer's diseaseBriefsPhase 3 Trial