AbbVie, RegenXBio Ink $1.75B Retinal Gene Therapy Collaboration


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  • AbbVie Inc (NYSE:ABBV) and Regenxbio Inc (NASDAQ:RGNX) have partnered to develop and commercialize RGX-314, potential one-time gene therapy for wet age-related macular degeneration (wet AMD), diabetic retinopathy (DR), and other chronic retinal diseases. 
  • RGX-314 is currently being evaluated in patients with wet AMD in a pivotal trial utilizing subretinal delivery and patients with wet AMD and DR in two separate Phase 2 trials using in-office suprachoroidal delivery. 
  • Read Next: Regenxbio Gene Therapy Shows Treatment Benefit In Wet AMD Study.
  • Under the collaboration, Regenxbio will complete the ongoing trials of RGX-314. AbbVie and Regenxbio will collaborate and share costs on additional trials of RGX-314.
  • AbbVie will lead the clinical development and commercialization of RGX-314 globally. 
  • Under the terms of the agreement, AbbVie will pay Regenxbio a $370 million upfront payment with the potential of up to $1.38 billion in milestone payments. 
  • Price Action: RGNX stock is trading 21.50% higher at $40.19, and ABBV stock is up 0.88% at $107.62 during the premarket session on the last check Monday.

Crypto Whales Are Loading Up — Are You?

New research shows the biggest crypto buyers are back. And this time? They could hold for the possibility that Bitcoin will surpass $100,000 in 2024. You don’t want to miss the next massive crypto bull run like we saw in 2020 and 2021. To know exactly what’s going on and what to buy… Get Access To Benzinga’s Best Crypto Research and Investments For Only $1.


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Posted In: BiotechNewsHealth CareContractsSmall CapMoversTrading IdeasGeneralAge-Related Macular DegenerationBriefsgene therapy