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- Adaptimmune Therapeutics plc (NASDAQ:ADAP) has announced a collaboration and license agreement with Genentech, a unit of Roche Holdings AG (OTC:RHHBY), to develop and commercialize allogeneic cell therapies for oncology indications.
- The collaboration includes developing allogeneic T-cell therapies for up to five shared cancer targets and personalized allogeneic T-cell therapies.
- Adaptimmune will be responsible for developing candidates using its induced pluripotent stem cell (iPSC) derived allogeneic platform to produce T-cells (iT cells).
- Genentech will be responsible for the input TCRs and subsequent clinical development and commercialization.
- Under the terms of the agreement, Adaptimmune will receive an upfront payment of $150 million and additional payments of $150 million over five years.
- In addition, Adaptimmune may be eligible to receive research, development, regulatory, and commercial milestones payments potentially exceeding $3 billion in aggregate value.
- Adaptimmune will also receive tiered royalties on net sales in the mid-single to low-double digits.
- Adaptimmune has the right to opt-in to a 50/50 U.S. profit/cost share on "off-the-shelf" products.
- Price Action: ADAP shares are up 27.1% at $6.28 during the premarket session on the last check Tuesday.
Crypto Whales Are Loading Up — Are You?
New research shows the biggest crypto buyers are back. And this time? They could hold for the possibility that Bitcoin will surpass $100,000 in 2024. You don’t want to miss the next massive crypto bull run like we saw in 2020 and 2021. To know exactly what’s going on and what to buy… Get Access To Benzinga’s Best Crypto Research and Investments For Only $1.
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