Jefferies Downgrades La Jolla On Weak Forecast For Blood Pressure Drug


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In the absence of a potential buyout, the downside risk for La Jolla Pharmaceutical Company (NASDAQ:LJPC) is greater than the upside potential in the next two to three years, according to Jefferies. 

The Analyst

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Jefferies analyst Eun Yang downgraded La Jolla from Buy to Underperform and lowered the price target from $40 to $29, suggesting 21-percent downside from current levels.

The Thesis

Polls with critical care physicians and pharmacy and therapeutics committee members showed only a modest sales opportunity for Giapreza, La Jolla's drug for low blood pressure, Yang said in a Monday note.

The Giapreza poll results point to 20- and 30-percent penetration of Giapreza in 2L and 3L, respectively, translating to a peak U.S. sales estimates of $324 million versus a prior estimate of $535 million, according to Jefferies.

The difference is due to lower transaction cost — $4,500 rather than the previous $8,000 — and a slightly higher number of patients. 


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La Jolla shares have gained 15 percent year-to-date compared to a 1-percent drop for the Nasdaq Biotechnology Index.

In December, HC Wainwright initiated coverage of La Jolla with a Buy rating and a $62 price target, citing a Feb. 28 PDUFA date for LJPC-501, a treatment candidate for vasodilatory shock.

The Price Action

La Jolla shares are up about 90 percent over the past year.

Shares were sliding more than 7 percent percent to $34.21 Monday morning. 

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27% profit every 20 days?

This is what Nic Chahine averages with his option buys. Not selling covered calls or spreads… BUYING options. Most traders don’t even have a winning percentage of 27% buying options. He has an 83% win rate. Here’s how he does it.


Posted In: Analyst ColorDowngradesPrice TargetAnalyst RatingsJefferies