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- Additional readouts from Valneva SE's (NASDAQ:VALN) pivotal VLA2001-301 "Cov-Compare" trial of COVID-19 vaccine VLA2001 showed persistent and first positive heterologous booster results following AstraZeneca Plc's (NASDAQ:AZN) COVID-19 primary vaccination.
- After two months, neutralizing antibody titers induced by VLA2001 was non-inferior to AstraZeneca's COVID shot (ChAdOx1-S).
- GMT was 444.0, and ChAdOx1-S GMT was 411.8.
- Related: Valneva Cuts FY22 COVID-19 Vaccine Sales Outlook, Needs Funding To Invest In Next-Gen COVID-19 Shot.
- Seroconversion rates remained constant (above 92% in both treatment groups).
- Additionally, approximately six months after primary vaccination showed that VLA2001 induced broad antigen-specific IFN-gamma-producing T-cells reactive against the S-protein and the N- and M-proteins.
- The safety profile of VLA2001 continues to be favorable, and the vaccine was well tolerated.
- The occurrence of COVID-19 cases was similar between the VLA2001 and ChAdOx1-S groups.
- Neutralizing antibody titers following a VLA2001 booster dose administered approximately eight months after primary vaccination were between 3-fold (heterologous) to 28-fold (homologous) higher than pre-boost levels, in line with previous VLA2001 Phase 1/2 homologous booster results.
- Price Action: VALN shares closed at $18.03 on Friday.
Crypto Whales Are Loading Up — Are You?
New research shows the biggest crypto buyers are back. And this time? They could hold for the possibility that Bitcoin will surpass $100,000 in 2024. You don’t want to miss the next massive crypto bull run like we saw in 2020 and 2021. To know exactly what’s going on and what to buy… Get Access To Benzinga’s Best Crypto Research and Investments For Only $1.
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