Merck-Eisai's Keytruda/Lenvima Combo Scores Japanese Approval For Kidney Cancer Setting


20-Year Pro Trader Reveals His "MoneyLine"

Ditch your indicators and use the "MoneyLine". A simple line tells you when to buy and sell without the guesswork. It’s a line on a chart that’s helped Nic Chahine win 83% of his options buys. Here's how he does it.


The Japanese Ministry of Health, Labour, and Welfare (MHLW) has approved Merck & Co Inc's (NYSE:MRK) Keytruda/Lenvima combo therapy for radically unresectable or metastatic renal cell carcinoma (RCC). 

  • Lenvima is an orally available multiple receptor tyrosine kinase inhibitor discovered by Eisai Co Ltd (OTC:ESALY).
  • Keytruda Plus Lenvima is also approved in the U.S. and Europe for the first-line treatment of adult patients with advanced RCC. 
  • This marks the second approval of this combination in Japan; in December 2021, Keytruda/Lenvima combo was approved for unresectable, advanced, or recurrent endometrial carcinoma that progressed after chemotherapy.
  • The approval is based on the pivotal Phase 3 CLEAR (Study 307)/KEYNOTE-581 trial. 
  • Keytruda plus Lenvima demonstrated statistically significant improvements versus sunitinib in the primary efficacy outcome of progression-free survival (PFS). 
  • Results showed Keytruda + Lenvima (n=355) reduced the risk of disease progression or death by 61%, with a median PFS of 23.9 months versus 9.2 months for sunitinib (n=357).
  • Price Action: MRK shares are up 0.30% at $73.73 during the premarket session on the last check Friday.

20-Year Pro Trader Reveals His "MoneyLine"

Ditch your indicators and use the "MoneyLine". A simple line tells you when to buy and sell without the guesswork. It’s a line on a chart that’s helped Nic Chahine win 83% of his options buys. Here's how he does it.


ENTER TO WIN $500 IN STOCK OR CRYPTO

Enter your email and you'll also get Benzinga's ultimate morning update AND a free $30 gift card and more!

Posted In: BiotechNewsHealth CareGeneralBriefs