BeiGene - EUSA Pharma's Siltuximab Approved In China For Multicentric Castleman Disease


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The China National Medical Products Administration has approved BeiGene Ltd (NASDAQ:BGNE) / EUSA Pharma (UK) Ltd's Sylvant (siltuximab) for adult patients with multicentric Castleman disease (MCD), also known as idiopathic MCD (iMCD).

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  • The approval covers patients who are human immunodeficiency virus (HIV) negative and human herpes virus-8 (HHV-8) negative.
  • The disease is a condition of the lymph nodes and related tissues. The Company plans to launch the treatment in 2022.
  • Phase 2 trial results supported the approval of siltuximab. There was a statistically significant difference in independently reviewed durable tumor and symptomatic response rate in the siltuximab arm compared with the placebo arm (34% vs. 0%, respectively).
  • An open-label, long-term extension Phase 2 trial was also conducted. 
  • The median duration of siltuximab treatment was 5.52 years (range: 0.8 to 10.8 years); more than 50% of patients received siltuximab treatment for ≥5 years. 
  • The rate of severe adverse events did not increase over time due to cumulative exposure.
  • Siltuximab is a monoclonal antibody that directly neutralizes IL-6, an inflammatory cytokine detected at elevated levels in multiple inflammatory conditions.
  • Price Action: BGNE shares are up 0.04% at $346.01 during the premarket session on the last check Friday.

27% profit every 20 days?

This is what Nic Chahine averages with his option buys. Not selling covered calls or spreads… BUYING options. Most traders don’t even have a winning percentage of 27% buying options. He has an 83% win rate. Here’s how he does it.


Posted In: BiotechNewsHealth CareGeneralBriefs