CEL-SCI's Immunotherapy Achieves Survival Benefit Of 14% Exceeding Pre-Defined 10% In Head & Cancer Patients


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  • CEL-SCI Corporation (NYSE:CVMhas announced results from its Phase 3 study for its immunotherapy Multikine for advanced previously untreated squamous cell carcinoma of the head and neck (SCCHN).
  • In the intent to treat patients, the study showed a statistically significant overall survival benefit of 14.1% with overall survival of 62.7% at five years for the group of patients receiving the Multikine treatment regimen followed by surgery and radiotherapy therapy, but not chemotherapy, as part of their standard of care treatment. 
  • The 3-year survival advantage was 4.9% (72.4% vs. 67.5%), and the 5-year survival advantage was 14.1% (62.7% vs. 48.6%) for the pre-defined population receiving no chemotherapy, versus standard of care alone.
  • No safety issues for Multikine were found during or due to its administration, including no late effects, in the overall treated patient population.
  • Multikine (Leukocyte Interleukin, Injection) is investigational cancer immunotherapy that contains 14 natural human cytokines, the body's immune system regulators.
  • Price Action: CVM shares are down 8.73% at $22.89 during the market session on the last check Monday.

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Posted In: BiotechNewsHealth CareSmall CapGeneralBriefsneck cancerPhase 3 Trial