AstraZeneca's Type 2 Diabetes Treatment Shows Clinical Benefit In Adolescents


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  • AstraZeneca Plc (NASDAQ:AZNhas reported results from the Phase 3 trial evaluating exenatide extended-release 2mg in adolescents aged 10–17 years with type 2 diabetes.
  • This once-weekly glucagon-like peptide-1 receptor agonist significantly reduced blood sugar, as measured by HbA1c, versus placebo.
  • The results were presented at the 2021 American Diabetes Association Scientific Sessions.
  • The trial met its primary endpoint, demonstrating that exenatide reduced HbA1c from baseline compared with placebo at 24 weeks, with mean changes of −0.36% and +0.49%, respectively.
  • Data at week 24 also showed that exenatide was generally well tolerated and consistent with the existing safety profile in adults. 
  • The most common adverse events were upper respiratory tract infections (10% in the exenatide group) and abdominal pain (13% in the placebo group). 
  • Gastrointestinal disorders were reported less frequently in the exenatide once weekly group than in the placebo group (22% vs. 26%).
  • The FDA granted AstraZeneca a priority review for its supplemental application to use exenatide in adolescents 10–17 years old.
  • In the US, exenatide is currently indicated as an adjunct to diet and exercise to improve glycemic control in adults with T2D.
  • Price Action: AZN shares are up 1.06% at $59.04 during the market trading session on the last check Friday.

27% profit every 20 days?

This is what Nic Chahine averages with his option buys. Not selling covered calls or spreads… BUYING options. Most traders don’t even have a winning percentage of 27% buying options. He has an 83% win rate. Here’s how he does it.


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Posted In: BiotechNewsHealth CareFDAGeneralBriefsPhase 3 TrialType 2 Diabetes