Pfizer/BioNTech Initiates COVID-19 Vaccine Trial In Children Below 12 Years: Reuters


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  • Pfizer Inc (NYSE:PFE) - BioNTech SE (NASDAQ:BNTX) will begin testing its COVID-19 vaccine in a bigger group of children under age 12 after selecting a lower dose shot in an earlier stage of the trial.
  • The study will enroll up to 4,500 children at more than 90 clinical sites, Reuters reported.
  • Based on safety, tolerability, and the immune response generated by 144 children in a Phase 1 study, Pfizer will test a dose of 10 micrograms in children between 5 and 11 years of age and 3 micrograms for the age group of 6 months to 5.
  • The vaccine has been authorized for use in children as young as 12 in Europe, the U.S., and Canada, and they receive the same dose of 30 micrograms as adults.
  • Still, researchers are studying the possibility of a link between heart inflammation and mRNA vaccines, particularly in young men. Both PFE/BNTX and Moderna Inc's (NASDAQ:MRNA) vaccines are mRNA shots.
  • Last week, Israel's Health Ministry said it had found a small number of myocarditis cases observed mainly in young men who received the Pfizer vaccines. The cases were generally mild and short-lasting.
  • Price Action: PFE shares are down 0.55% at $38.78, and BNTX shares are down 6.6% at $222.47 during the market session on the last check Tuesday.

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Posted In: BiotechGovernmentNewsHealth CareFDAGeneralBriefsCOVID-19 VaccineReuters