Delcath Systems' Hepzato Achieves 44% Best Overall Response Compared to Best Alternative Care in Eye Cancer


27% profit every 20 days?

This is what Nic Chahine averages with his option buys. Not selling covered calls or spreads… BUYING options. Most traders don’t even have a winning percentage of 27% buying options. He has an 83% win rate. Here’s how he does it.


  • Delcath Systems Inc (NASDAQ:DCTH) has announced positive preliminary efficacy results from its FOCUS Phase 3 trial evaluating Hepzato Kit (melphalan hydrochloride for injection/hepatic delivery system) in patients with liver dominant metastatic ocular melanoma.
  • Data were presented at the American Society of Clinical Oncology Annual Meeting.
  • Data showed that 44% of evaluable patients in the Hepzato arm had a 30% or greater reduction in target tumor lesions at one or more time points versus 17% for patients enrolled in the Best Alternative Care (BAC) arm.
  • Hepzato Kit, percutaneous hepatic perfusion (PHP) system showed preliminary overall response rate nearly three times better versus BAC arm in both treated (32.9% vs. 13.8%) and preliminary intent to treat - ITT (29.2% vs. 10.3%).
  • The preliminary disease control rate was approximately doubled in favor of PHP vs. BAC in both treated (71% vs. 38%) and preliminary ITT (63% vs. 29%).
  • Preliminary progression-free survival was nearly tripled in PHP vs. BAC (9.03 months vs. 3.06 months).
  • Data also covered previously announced preliminary data showing an overall response rate of 29.2% with a 95% confidence interval lower bound of 20%. Given the magnitude by which the lower bound exceeds the 8.3% prespecified threshold for success.
  • As 57.1% of the subjects in the BAC arm were able to crossover to the PHP arm, this crossover design of the study, the overall survival benefit was confounded.
  • On the safety front, the most common treatment-related severe adverse events were thrombocytopenia (14.9%), neutropenia (10.9%), and leukopenia (4.2%).
  • See the slide presentation here.
  • Price Action: DCTH shares are up 3.21% at $11.05 during the market session on the last check Monday.

27% profit every 20 days?

This is what Nic Chahine averages with his option buys. Not selling covered calls or spreads… BUYING options. Most traders don’t even have a winning percentage of 27% buying options. He has an 83% win rate. Here’s how he does it.


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Posted In: BiotechNewsHealth CareFDAGeneralBriefseye cancer