AC Immune's Alzheimer's Vaccine Candidate Elicit Response In Early-Stage Study; Shares Rally


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  • AC Immune SA (NASDAQ: ACIU) soars in premarket on robust volume, on the heels of positive interim results from its ongoing Phase 1b/2a trial evaluating its anti-phospho-Tau (pTau) vaccine candidate ACI-35.030 for the treatment of Alzheimer's disease.
  • ACI-35.030 is under development in collaboration with Johnson & Johnson's (NYSE:JNJ) Janssen Pharmaceuticals under a 2014 agreement.
  • Data shows that after the first injection of ACI-35.030, both lowest and second highest dosages, 100% of the patients demonstrated a potent antigen-specific antibody response against pTau, achieving antibody levels much higher than pre-vaccination levels. It does not show clinically relevant adverse events.
  • The company says that anti-pTau vaccination generates antibody responses with pharmacokinetic characteristics and target epitopes that differ substantially from the company's anti-Tau monoclonal antibody semorinemab.
  • The third and highest dosing group, per the study protocol, is up next.
  • The 32-subject trial's primary objective is to assess the safety, tolerability, and immunogenicity of different doses of ACI-35.030 over a 48-week in patients with early AD. Other endpoints will assess clinical and cognitive parameters as well as additional immunogenicity and safety parameters.
  • Price Action: ACIU gained 117.7% at $15.87 in premarket trading on the last check Thursday.

27% profit every 20 days?

This is what Nic Chahine averages with his option buys. Not selling covered calls or spreads… BUYING options. Most traders don’t even have a winning percentage of 27% buying options. He has an 83% win rate. Here’s how he does it.


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Posted In: BiotechNewsSmall CapFDATop StoriesGeneralAlzheimer’sJanssen PharmaceuticalsPhase 1 Trial