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Alnylam Pharmaceuticals Inc has a consensus price target of $461 based on the ratings of 32 analysts. The high is $583 issued by Citigroup on September 2, 2025. The low is $310 issued by Bernstein on January 7, 2025. The 3 most-recent analyst ratings were released by Citigroup, HC Wainwright & Co., and RBC Capital on May 19, 2026, May 5, 2026, and May 1, 2026, respectively. With an average price target of $445 between Citigroup, HC Wainwright & Co., and RBC Capital, there's an implied 50.22% upside for Alnylam Pharmaceuticals Inc from these most-recent analyst ratings.
1calculated from analyst ratings
The latest price target for Alnylam Pharmaceuticals (NASDAQ:ALNY) was reported by Citigroup on May 19, 2026. The analyst firm set a price target for $380.00 expecting ALNY to rise to within 12 months (a possible 28.27% upside). 66 analyst firms have reported ratings in the last year.
The latest analyst rating for Alnylam Pharmaceuticals (NASDAQ:ALNY) was provided by Citigroup, and Alnylam Pharmaceuticals initiated their buy rating.
The last upgrade for Alnylam Pharmaceuticals Inc happened on February 17, 2026 when Freedom Broker raised their price target to $410. Freedom Broker previously had a hold for Alnylam Pharmaceuticals Inc.
The last downgrade for Alnylam Pharmaceuticals Inc happened on March 16, 2026 when Jefferies changed their price target from $522 to $330 for Alnylam Pharmaceuticals Inc.
Analysts arrive at stock ratings after doing extensive research, which includes going through public financial statements, talking to executives and customers of Alnylam Pharmaceuticals, and listening in to earnings conference calls. Most analysts do this every three months, so you should get 4 ratings per company per firm each year. The last rating for Alnylam Pharmaceuticals was filed on May 19, 2026 so you should expect the next rating to be made available sometime around May 19, 2027.
While ratings are subjective and will change, the latest Alnylam Pharmaceuticals (ALNY) rating was a initiated with a price target of $0.00 to $380.00. The current price Alnylam Pharmaceuticals (ALNY) is trading at is $296.24, which is within the analyst’s predicted range.
Browse analyst ratings and price targets on all stocks.
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| Buy Now | Get Alert | ||||||
|---|---|---|---|---|---|---|---|
| 05/19/2026 | Buy Now | 28.27% | Citigroup | → $380 | Initiates | → Buy | Get Alert |
| 05/05/2026 | Buy Now | 72.16% | HC Wainwright & Co. | $510 → $510 | Reiterates | Buy → Buy | Get Alert |
| 05/01/2026 | Buy Now | 50.22% | RBC Capital | $450 → $445 | Maintains | Outperform | Get Alert |
| 05/01/2026 | Buy Now | 27.26% | Wells Fargo | $376 → $377 | Maintains | Equal-Weight | Get Alert |
| 04/13/2026 | Buy Now | 70.47% | Truist Securities | $515 → $505 | Maintains | Buy | Get Alert |
| 03/25/2026 | Buy Now | 43.46% | Chardan Capital | $425 → $425 | Maintains | Buy | Get Alert |
| 03/25/2026 | Buy Now | 72.16% | HC Wainwright & Co. | $510 → $510 | Reiterates | Buy → Buy | Get Alert |
| 03/16/2026 | Buy Now | 11.4% | Jefferies | $522 → $330 | Downgrade | Buy → Hold | Get Alert |
| 02/18/2026 | Buy Now | 72.16% | HC Wainwright & Co. | $510 → $510 | Reiterates | Buy → Buy | Get Alert |
| 02/17/2026 | Buy Now | 38.4% | Freedom Broker | $470 → $410 | Upgrade | Hold → Buy | Get Alert |
| 02/17/2026 | Buy Now | 44.82% | Canaccord Genuity | $415 → $429 | Maintains | Buy | Get Alert |
| 02/13/2026 | Buy Now | 43.46% | Chardan Capital | $475 → $425 | Maintains | Buy | Get Alert |
| 02/12/2026 | Buy Now | 72.16% | Needham | $529 → $510 | Maintains | Buy | Get Alert |
| 01/30/2026 | Buy Now | 37.73% | Morgan Stanley | $495 → $408 | Maintains | Equal-Weight | Get Alert |
| 01/30/2026 | Buy Now | 55.95% | B of A Securities | $529 → $462 | Maintains | Buy | Get Alert |
| 01/30/2026 | Buy Now | 72.16% | HC Wainwright & Co. | $570 → $510 | Maintains | Buy | Get Alert |
| 01/28/2026 | Buy Now | 77.9% | Barclays | → $527 | Initiates | → Overweight | Get Alert |
| 01/20/2026 | Buy Now | 56.97% | RBC Capital | $500 → $465 | Maintains | Outperform | Get Alert |
| 01/20/2026 | Buy Now | 26.92% | Wells Fargo | $479 → $376 | Maintains | Equal-Weight | Get Alert |
| 01/12/2026 | Buy Now | 78.57% | B of A Securities | $530 → $529 | Maintains | Buy | Get Alert |
| 01/12/2026 | Buy Now | 78.57% | Needham | $520 → $529 | Maintains | Buy | Get Alert |
| 01/08/2026 | Buy Now | 78.91% | Truist Securities | $535 → $530 | Maintains | Buy | Get Alert |
| 12/15/2025 | Buy Now | 18.49% | Leerink Partners | $370 → $351 | Maintains | Market Perform | Get Alert |
| 12/11/2025 | Buy Now | 71.48% | Stifel | $495 → $508 | Maintains | Buy | Get Alert |
| 11/11/2025 | Buy Now | 61.69% | Wells Fargo | $395 → $479 | Maintains | Equal-Weight | Get Alert |
| 11/05/2025 | Buy Now | 58.66% | Freedom Broker | $230 → $470 | Maintains | Buy | Get Alert |
| 10/31/2025 | Buy Now | 65.07% | Piper Sandler | $449 → $489 | Reiterates | Overweight → Overweight | Get Alert |
| 10/31/2025 | Buy Now | 77.9% | Barclays | $460 → $527 | Maintains | Overweight | Get Alert |
| 10/30/2025 | Buy Now | 85.32% | Jefferies | $550 → $549 | Maintains | Buy | Get Alert |
| 10/17/2025 | Buy Now | 80.6% | Truist Securities | $459 → $535 | Maintains | Buy | Get Alert |
| 10/13/2025 | Buy Now | 59.67% | JP Morgan | $475 → $473 | Maintains | Overweight | Get Alert |
| 10/10/2025 | Buy Now | 92.41% | HC Wainwright & Co. | $570 → $570 | Reiterates | Buy → Buy | Get Alert |
| 10/06/2025 | Buy Now | 60.34% | Morgan Stanley | $405 → $475 | Maintains | Equal-Weight | Get Alert |
| 10/06/2025 | Buy Now | 67.09% | Stifel | $441 → $495 | Maintains | Buy | Get Alert |
| 09/19/2025 | Buy Now | 68.78% | RBC Capital | $435 → $500 | Maintains | Outperform | Get Alert |
| 09/17/2025 | Buy Now | 75.53% | B of A Securities | $453 → $520 | Maintains | Buy | Get Alert |
| 09/16/2025 | Buy Now | 91.06% | Goldman Sachs | $504 → $566 | Maintains | Buy | Get Alert |
| 09/15/2025 | Buy Now | 85.66% | Jefferies | $453 → $550 | Maintains | Buy | Get Alert |
| 09/11/2025 | Buy Now | 73.86% | Evercore ISI Group | $280 → $515.05 | Maintains | Outperform | Get Alert |
| 09/08/2025 | Buy Now | 58.66% | BMO Capital | $450 → $470 | Maintains | Outperform | Get Alert |
| 09/02/2025 | Buy Now | 92.41% | HC Wainwright & Co. | $570 → $570 | Reiterates | Buy → Buy | Get Alert |
| 09/02/2025 | Buy Now | 96.8% | Citigroup | $527 → $583 | Maintains | Buy | Get Alert |
| 08/07/2025 | Buy Now | 92.41% | HC Wainwright & Co. | $500 → $570 | Maintains | Buy | Get Alert |
| 08/06/2025 | Buy Now | 60.34% | JP Morgan | $348 → $475 | Maintains | Overweight | Get Alert |
| 08/04/2025 | Buy Now | 65.41% | Oppenheimer | → $490 | Upgrade | Perform → Outperform | Get Alert |
| 08/04/2025 | Buy Now | — | Wolfe Research | — | Upgrade | Underperform → Peer Perform | Get Alert |
| 08/01/2025 | Buy Now | 51.9% | Scotiabank | $342 → $450 | Maintains | Sector Outperform | Get Alert |
| 08/01/2025 | Buy Now | 85.66% | UBS | $403 → $550 | Maintains | Buy | Get Alert |
| 08/01/2025 | Buy Now | 40.09% | Canaccord Genuity | $390 → $415 | Maintains | Buy | Get Alert |
| 08/01/2025 | Buy Now | 33.34% | Wells Fargo | $333 → $395 | Maintains | Equal-Weight | Get Alert |
| 08/01/2025 | Buy Now | 43.13% | Raymond James | $370 → $424 | Reiterates | Outperform → Outperform | Get Alert |
| 08/01/2025 | Buy Now | 55.28% | Barclays | $329 → $460 | Maintains | Overweight | Get Alert |
| 08/01/2025 | Buy Now | 51.57% | Piper Sandler | $304 → $449 | Maintains | Overweight | Get Alert |
| 08/01/2025 | Buy Now | 35.03% | Chardan Capital | $325 → $400 | Maintains | Buy | Get Alert |
| 08/01/2025 | Buy Now | 36.71% | Morgan Stanley | $312 → $405 | Maintains | Equal-Weight | Get Alert |
| 07/31/2025 | Buy Now | 61.36% | Needham | $377 → $478 | Maintains | Buy | Get Alert |
| 07/29/2025 | Buy Now | 24.9% | Raymond James | $308 → $370 | Assumes | Outperform → Outperform | Get Alert |
| 07/21/2025 | Buy Now | 29.96% | Truist Securities | → $385 | Initiates | → Buy | Get Alert |
| 07/16/2025 | Buy Now | 17.47% | JP Morgan | $338 → $348 | Maintains | Overweight | Get Alert |
| 07/11/2025 | Buy Now | 36.38% | Citigroup | $364 → $404 | Maintains | Buy | Get Alert |
| 07/11/2025 | Buy Now | 21.19% | B of A Securities | $336 → $359 | Maintains | Buy | Get Alert |
| 07/07/2025 | Buy Now | 29.62% | Jefferies | $328 → $384 | Maintains | Buy | Get Alert |
| 06/30/2025 | Buy Now | 12.41% | Wells Fargo | $287 → $333 | Maintains | Equal-Weight | Get Alert |
| 06/26/2025 | Buy Now | 27.26% | Needham | $320 → $377 | Maintains | Buy | Get Alert |
| 06/24/2025 | Buy Now | 21.52% | BMO Capital | $300 → $360 | Maintains | Outperform | Get Alert |
| 06/12/2025 | Buy Now | 14.1% | JP Morgan | $330 → $338 | Maintains | Overweight | Get Alert |
| 05/02/2025 | Buy Now | 17.81% | UBS | $331 → $349 | Maintains | Buy | Get Alert |
| 05/02/2025 | Buy Now | 9.71% | Chardan Capital | $300 → $325 | Maintains | Buy | Get Alert |
| 04/11/2025 | Buy Now | -9.53% | Morgan Stanley | $284 → $268 | Maintains | Equal-Weight | Get Alert |
| 04/09/2025 | Buy Now | 8.02% | Needham | $320 → $320 | Reiterates | Buy → Buy | Get Alert |
| 04/02/2025 | Buy Now | 68.78% | HC Wainwright & Co. | $500 → $500 | Reiterates | Buy → Buy | Get Alert |
| 03/31/2025 | Buy Now | 15.45% | Scotiabank | $338 → $342 | Maintains | Sector Outperform | Get Alert |
| 03/31/2025 | Buy Now | 19.16% | Redburn Atlantic | → $353 | Initiates | → Buy | Get Alert |
| 03/31/2025 | Buy Now | 16.46% | Stifel | $300 → $345 | Maintains | Buy | Get Alert |
| 03/24/2025 | Buy Now | 10.72% | JP Morgan | $280 → $328 | Upgrade | Neutral → Overweight | Get Alert |
| 03/21/2025 | Buy Now | 18.49% | Citigroup | $338 → $351 | Maintains | Buy | Get Alert |
| 03/21/2025 | Buy Now | 31.65% | Canaccord Genuity | $385 → $390 | Maintains | Buy | Get Alert |
| 03/21/2025 | Buy Now | 11.4% | RBC Capital | $310 → $330 | Maintains | Outperform | Get Alert |
| 03/21/2025 | Buy Now | 14.1% | Scotiabank | $300 → $338 | Maintains | Sector Outperform | Get Alert |
| 03/21/2025 | Buy Now | -3.12% | Wells Fargo | $275 → $287 | Maintains | Equal-Weight | Get Alert |
| 03/21/2025 | Buy Now | 9.71% | B of A Securities | $302 → $325 | Maintains | Buy | Get Alert |
| 03/21/2025 | Buy Now | 1.27% | Chardan Capital | $300 → $300 | Maintains | Buy | Get Alert |
| 03/21/2025 | Buy Now | 8.02% | Needham | $320 → $320 | Reiterates | Buy → Buy | Get Alert |
| 03/11/2025 | Buy Now | -5.48% | JP Morgan | $272 → $280 | Maintains | Neutral | Get Alert |
| 02/26/2025 | Buy Now | 4.64% | RBC Capital | $310 → $310 | Reiterates | Outperform → Outperform | Get Alert |
| 02/26/2025 | Buy Now | 1.27% | Chardan Capital | $300 → $300 | Maintains | Buy | Get Alert |
| 02/26/2025 | Buy Now | 8.02% | Needham | $320 → $320 | Reiterates | Buy → Buy | Get Alert |
| 02/25/2025 | Buy Now | 68.78% | HC Wainwright & Co. | $400 → $500 | Reiterates | Buy → Buy | Get Alert |
| 02/24/2025 | Buy Now | 68.78% | HC Wainwright & Co. | $400 → $500 | Maintains | Buy | Get Alert |
| 02/18/2025 | Buy Now | 29.96% | Canaccord Genuity | $384 → $385 | Maintains | Buy | Get Alert |
| 02/14/2025 | Buy Now | 1.27% | Scotiabank | $310 → $300 | Maintains | Sector Outperform | Get Alert |
| 02/14/2025 | Buy Now | -4.13% | Morgan Stanley | $275 → $284 | Maintains | Equal-Weight | Get Alert |
| 02/14/2025 | Buy Now | 8.02% | Needham | $320 → $320 | Reiterates | Buy → Buy | Get Alert |
| 02/11/2025 | Buy Now | 1.27% | RBC Capital | $300 → $300 | Reiterates | Outperform → Outperform | Get Alert |
| 01/21/2025 | Buy Now | 1.27% | RBC Capital | $300 → $300 | Reiterates | Outperform → Outperform | Get Alert |
| 01/13/2025 | Buy Now | 35.03% | HC Wainwright & Co. | $400 → $400 | Reiterates | Buy → Buy | Get Alert |
| 01/13/2025 | Buy Now | 8.02% | Needham | $320 → $320 | Reiterates | Buy → Buy | Get Alert |
| 01/07/2025 | Buy Now | 4.64% | Bernstein | $314 → $310 | Maintains | Outperform | Get Alert |
| 11/18/2024 | Buy Now | -0.08% | Piper Sandler | $296 → $296 | Reiterates | Overweight → Overweight | Get Alert |
| 11/18/2024 | Buy Now | 35.03% | HC Wainwright & Co. | $400 → $400 | Reiterates | Buy → Buy | Get Alert |