Bristol-Myers, Abbott Announce Results from Phase 2 Multiple Myeloma Study


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Bristol-Myers Squibb Company (NYSE: BMY) and Abbott (NYSE: ABT) today announced results from a small, randomized Phase 2, open-label study in patients with previously-treated multiple myeloma that evaluated two doses of elotuzumab (10 mg/kg and 20 mg/kg) in combination with lenalidomide and low-dose dexamethasone. In the 10 mg/kg arm, median progression-free survival (PFS), or the time without disease progression or death, was not reached after 20.8 months of follow up (N=36) and the objective response rate (ORR) was 92%. Of patients who received elotuzumab at a dose of 20 mg/kg, median PFS was 18.6 months (N=37) and ORR was 76%. The safety data are consistent with previously-reported results for

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