Oncolytics Announces Positive Phase 2 REOLYSIN Data

Oncolytics Biotech (NASDAQ: ONCY) today announced a poster presentation containing updated efficacy data from a Phase 2 study examining the use of REOLYSIN® in combination with carboplatin and paclitaxel in patients with stage IV non-small cell lung cancer (NSCLC) with Kras or EGFR-activated tumors (REO 016) was made at International Association for the Study of Lung Cancer (IASLC). The conference is being held from October 27th to 30th, 2013 in Sydney, Australia.The poster presentation included new efficacy data that correlated a number of molecular abnormalities with best response, progression free survival (PFS) and one-year survival. Current data in these patients demonstrates that 20 of 36 evaluable patients (56%) survived a year or more. There were 13 patients with only EGFR mutations or amplifications, of whom nine (69.2%) survived a year or longer. Four of four (100%) patients with BRAF and EGFR amplification survived a year or longer."This is the first time we have reported data correlating the presence of specific biomarkers with efficacy, which covers both best response and survival in patient tumours with a Ras-activated pathway," said Dr. Brad Thompson, President and CEO of Oncolytics. "Although the study examined a See full press release