SAN DIEGO--(BUSINESS WIRE)--
At the Sixth AFM BioMed Conference, Bruker (NASDAQ: BRKR) today
announced the release of BioScope
Resolve™, a biological atomic force microscope (bioAFM) that
features the highest resolution imaging and most complete cell mechanics
capabilities available for use with an inverted optical microscope
(IOM). The system incorporates Bruker's proprietary PeakForce
Tapping® technology to enable researchers to achieve both the
highest resolution imaging and piconewton level force measurements on
biological samples. BioScope Resolve also provides
real-time correlation of atomic force microscopy and optical microscopy
data sets to provide unique insights into life sciences research.
Ultimately, BioScope Resolve enables imaging and
mechanical property mapping of the biological detail of cells, tissues,
and biomolecular structures never previously observed with a bioAFM on
an IOM.
Bruker's BioScope Resolve enables unrivalled bioAFM imaging resolution and cell mechanics capabilities on an inverted optical microscope. (Photo: Business Wire)
“For the first time bioAFM analysis can directly correlate
high-resolution molecular structures with function on the same cell,”
said Dr. Lewis Francis of the College of Medicine and Center of
NanoHealth at Swansea University, United Kingdom. “BioScope Resolve
provides the dynamic range and resolution necessary to allow a deeper
understanding of structure-function relationships at cell and tissue
surfaces.”
“BioScope Resolve establishes a new benchmark for
high-resolution imaging and cell mechanics characterization capabilities
that are fully integrated with optical microscopy,” added David V.
Rossi, Executive Vice President and General Manager of Bruker's AFM
business. “It builds upon our exclusive and leading PeakForce Tapping
technology to enable the highest performance bioAFM that researchers of
every experience level will find very easy to use.”
“PeakForce Tapping provided my lab with the force control and resolution
necessary to produce ground-breaking ligand-receptor interaction maps
using functionalized probes on live cells in a very time efficient and
controlled way,” commented Professor Dr. Daniel Muller of the Department
of Biosystems Science and Engineering at the ETH Zürich, Switzerland,
about his experience using PeakForce Tapping.
About BioScope Resolve
BioScope Resolve is an AFM developed specifically for
integration with optical microscopy for biological research into cells,
tissues and molecules. The new system provides the most complete range
of capabilities for cell mechanics and molecular force spectroscopy. Its
design enables the highest resolution imaging for all types of
biological samples, from cells to biomolecules, making it the new
benchmark in high-resolution bioAFM capability. In addition, BioScope
Resolve has complete synchronization with the top inverted
optical microscope brands, and provides single-button imaging using
proprietary ScanAsyst®
technology. Researchers can utilize the system's quantitative PeakForce
QNM® nanomechanics package to map the surfaces of soft biological
samples. BioScope Resolve's mechanical mapping
capabilities bridge Force Volume and PeakForce QNM frequencies for the
widest range available for force-distance curves on any AFM. BioScope
Resolve also offers a full array of accessories to preserve the
integrity of delicate samples, including carrier support with clear
visual and physical access to samples, environmental control with
heating and cooling capabilities, and a wide range of pre-calibrated
biological probes.
About Bruker Corporation
Bruker Corporation is a leading provider of high-performance scientific
instruments and solutions for molecular, cellular and materials
research, as well as for industrial, diagnostics, clinical research and
applied analysis. For more information about Bruker Corporation, please
visit www.bruker.com.
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