Ocuphire is a publicly traded (NASDAQ: OCUP), clinical-stage ophthalmic biopharmaceutical company focused on developing and commercializing therapies for the treatment of several eye disorders. Ocuphire’s pipeline currently includes two small-molecule product candidates targeting front and back of the eye indications. The company’s lead product candidate, Nyxol® (0.75% phentolamine ophthalmic solution) Eye Drops, is a once-daily preservative-free eye drop formulation of phentolamine mesylate, a non-selective alpha-1 and alpha-2 adrenergic antagonist designed to reduce pupil size, and is being developed for several indications, including reversal of pharmacologically-induced mydriasis (RM), presbyopia, and dim light or night vision disturbances (NVD), and has been studied in 9 clinical trials including the recently completed Phase 3 trial in RM and Phase 2 trial in presbyopia. Ocuphire reported positive topline data in March 2021 for MIRA-2, a Phase 3 FDA registration study for treatment of RM. Ocuphire also reported positive top-line data in June 2021 for VEGA-1, a Phase 2 trial for the treatment of presbyopia. Nyxol is also currently in Phase 3 clinical development for NVD. Ocuphire’s second product candidate, APX3330, is an oral tablet designed to inhibit angiogenesis and inflammation pathways relevant to retinal and choroidal vascular diseases, such as diabetic retinopathy (DR) and diabetic macular edema (DME) and has been studied in 11 Phase 1 and 2 trials. APX3330 is currently enrolling subjects in a Phase 2 clinical trial in subjects with DR/DME. As part of its strategy, Ocuphire will continue to explore opportunities to acquire additional ophthalmic assets and to seek strategic partners for late-stage development, regulatory preparation, and commercialization of drugs in key global markets. For more information, please visit www.ocuphire.com.
CEO & Founder
Mina Sooch is Founder, CEO and President of Ocuphire Pharma (Nasdaq: OCUP). With over 25 years of pharma and biotech experience as CEO, entrepreneur, venture capitalist, and strategist, Mina has successfully raised hundreds of millions of dollars for over 10 biotech companies and led 3 successful public Nasdaq listings. She was co-founder & CEO of Gemphire Therapeutics, a public, clinical-stage cardiovascular company as well as co-founder & CEO of ProNAi Therapeutics, a public, clinical-stage oncology company. Mina also co-founded in 2003 Apjohn Ventures Fund with a focus on early-stage life sciences companies. Earlier in her career, she served as a global account manager at Monitor Group, a top-tier global strategy consulting firm based in Boston. She has served on the boards of over 12 private, public, and nonprofit firms, and has been the recipient of numerous awards, including one of the 2016 Deal Makers of the year by Crain’s Detroit Business. Mina received an M.B.A. from Harvard Business School and a B.S. summa cum laude in Chemical Engineering from Wayne State University in Michigan.