Market Overview

Navidea Biopharmaceuticals to Present at the 12th Annual LD Micro Main Event

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Navidea Biopharmaceuticals, Inc. (NYSE:NAVB) ("Navidea" or the "Company"), a company focused on the development of precision immunodiagnostic agents and immunotherapeutics, today announced that Mr. Jed Latkin, Chief Executive Officer, will present at the 12th Annual LD Micro Main Event investor conference. The conference will be held at the Luxe Bel Air Hotel in Los Angeles, CA on December 10-12, 2019. Mr. Latkin will present on Wednesday, December 11 at 10:20 a.m. PT (1:20 p.m. ET) in Track 4, which will be webcast.

Details of Navidea's presentation are below. For those who wish to listen to the live webcast, please use the following link: http://wsw.com/webcast/ldmicro17/navb/. The webcast will be archived on Navidea's investor relations website, https://ir.navidea.com/news-events for 90 days following the live presentation.

Event:

12th Annual LD Micro Main Event

Date:

Wednesday, December 11, 2019

Time:

10:20 a.m. PT (1:20 p.m. ET)

Location:

Luxe Sunset Boulevard Hotel, Los Angeles, CA – Track 4

Webcast:

http://wsw.com/webcast/ldmicro17/navb/

The 12th Annual LD Micro Main Event will feature 275 emerging growth companies and is expected to attract 1,500 attendees. To schedule a one-on-one meeting with Mr. Latkin, please contact Adam Holdsworth at adamh@pcgadvisory.com.

About Navidea Biopharmaceuticals

Navidea Biopharmaceuticals, Inc. (NYSE:NAVB) is a biopharmaceutical company focused on the development of precision immunodiagnostic agents and immunotherapeutics. Navidea is developing multiple precision-targeted products based on its Manocept™ platform to enhance patient care by identifying the sites and pathways of disease and enable better diagnostic accuracy, clinical decision-making, and targeted treatment. Navidea's Manocept platform is predicated on the ability to specifically target the CD206 mannose receptor expressed on activated macrophages. The Manocept platform serves as the molecular backbone of Tc99m tilmanocept, the first product developed and commercialized by Navidea based on the platform. Navidea's strategy is to deliver superior growth and shareholder return by bringing to market novel products and advancing the Company's pipeline through global partnering and commercialization efforts.

For more information, please visit www.navidea.com.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. We have based these forward-looking statements largely on our current expectations and projections about future events and financial trends affecting the financial condition of our business. Forward looking statements include our expectations regarding pending litigation and other matters. These forward-looking statements are subject to a number of risks, uncertainties and assumptions, including, among other things: our history of losses and uncertainty of future profitability; the final outcome of any pending litigation (including the case described above); our ability to successfully complete research and further development of our drug candidates; the timing, cost and uncertainty of obtaining regulatory approvals of our drug candidates; our ability to successfully commercialize our drug candidates; dependence on royalties and grant revenue; our ability to implement our growth strategy; anticipated trends in our business; our limited product line and distribution channels; advances in technologies and development of new competitive products; our ability to comply with the NYSE American continued listing standards; our ability to maintain effective internal control over financial reporting; and other risk factors detailed in our most recent Annual Report on Form 10-K and other SEC filings. You are urged to carefully review and consider the disclosures found in our SEC filings, which are available at http://www.sec.gov or at http://ir.navidea.com.

Investors are urged to consider statements that include the words "will," "may," "could," "should," "plan," "continue," "designed," "goal," "forecast," "future," "believe," "intend," "expect," "anticipate," "estimate," "project," and similar expressions, as well as the negatives of those words or other comparable words, to be uncertain forward-looking statements.

You are cautioned not to place undue reliance on any forward-looking statements, any of which could turn out to be incorrect. We undertake no obligation to update publicly or revise any forward-looking statements, whether as a result of new information, future events or otherwise after the date of this report. In light of these risks and uncertainties, the forward-looking events and circumstances discussed in this report may not occur and actual results could differ materially from those anticipated or implied in the forward-looking statements.

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