DermTech Further Expands Patent Portfolio

DermTech, Inc. DMTK ("DermTech"), a global leader in precision dermatology enabled by a non-invasive skin genomics platform, announced today the issuance of patent, US 10,407,729, further expanding the company's intellectual property and leadership position.

This latest patent issued by the US Patent Office is entitled "Diagnosis of melanoma by nucleic acid analysis" and includes claims in connection with DermTech's technology to non-invasively obtain genomic information for characterizing skin lesions. The patent includes claims related to using expression levels of PRAME (also known as preferentially expressed antigen in melanoma, which is overexpressed in this type of cancer) to differentiate melanoma from non-melanoma skin samples obtained via the company's adhesive patch-based sample collection platform. DermTech has discovered that PRAME is a key gene in the assessment of melanoma using genomics.

"This patent expands on earlier work at DermTech and further highlights our ability to non-invasively obtain valuable genomic information, in this case on targets including PRAME, to support clinicians in their efforts to better serve patients with moles suspected of being melanomas. Our technology provides them with actionable genomic information that cannot be ascertained visually. Offering information on high value targets such as PRAME, and being able to do so without the need for surgical biopsies, carries the potential to transform the practice of dermatology," said Dr. Zuxu Yao, DermTech's Chief Scientific Officer.

About DermTech:

DermTech is a leader in the new category of medicine, precision dermatology. DermTech's mission is to transform the practice of dermatology through more accurate diagnosis and treatment, and the elimination of unnecessary surgery, leading to improved patient care and lower costs. DermTech provides genomic analysis of skin samples collected non-invasively using an adhesive patch rather than a scalpel. DermTech markets and develops products that facilitate the early detection of skin cancers, assess inflammatory diseases, and customize drug treatments. For additional information on DermTech, please visit DermTech's investor relations site at: www.DermTech.com

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