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Seq2Know Launches High Cholesterol Genetic Test


Seq2Know Launches High Cholesterol Genetic Test

PR Newswire

MARSHFIELD, Wis., Aug. 22, 2018 /PRNewswire/ -- Seq2Know, a consumer-initiated genetic testing service, is offering Familial Hypercholesterolemia (FH) testing. FH is a hereditary form of high cholesterol that increases the risk for heart disease and stroke, the first and fifth leading causes of death in the United States, respectively.  

Approximately one in six adults have high cholesterol (Schober et al, 2007); high cholesterol is caused by FH in about one in every 500 people in the US.  

Although over 30 million individuals may have FH, many are unaware of their risk (Sturm et al, 2018).  

The FH Foundations' Consensus Statement on Genetic Testing for FH recommends testing as a diagnosis offers the opportunity to prevent FH-related cardiovascular disease. Genetic testing is especially important for those with consistently high cholesterol, have had a heart attack at an early age, or have a family history of high cholesterol or early onset heart disease.

Dr. Mike Chicka, a Molecular Geneticist at Seq2Know, adds, "Since Seq2Know's test is accessible, comprehensive, and affordable, it can help identify undiagnosed individuals with FH, thereby mitigating risk."

Seq2Know's test includes sequencing of four important genes that cause FH (LDLR, APOB, PCSK9, LDLRAP1). All Seq2Know tests are ordered directly from and reviewed by an independent physician network, PWNHealth to ensure the test is appropriate for the individual.  Once testing is approved, individuals are sent a saliva kit to provide a specimen for testing.  After testing is complete, PWNHealth reviews the results and the individual is notified their results are available.  Seq2Know's FH test also includes access to genetic counseling through PWNHealth.

About Seq2Know

Seq2Know, a service of PreventionGenetics, LLC, is a high-quality, certified DNA testing laboratory offering genetic sequencing services to help people determine their genetic risk for hereditary disorders.

About PWNHealth

PWNHealth is a leading virtual care company enabling access to diagnostic testing, treatment and professional guidance that empowers individuals to improve their health. Using our physicians, genetic counselors, robust technology platform, and patient services center we provide services nationwide to a range of health industry customers.


Schober et al. High Serum Total Cholesterol – An Indicator for Monitoring Cholesterol Lowering Efforts: U.S. Adults, 2005–2006. Division of Health and Nutrition Examination Surveys. 2007.

Sturm, et al. Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert Panel. Journal of the American College of Cardiology.  2018 Aug 7;72(6):662-680.

Contact: Danielle Krohn, 1-715-387-0484 x257


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