Market Overview

Conavi Medical Announces Clinical Use of the Novasight Hybrid System with Simultaneous Intravascular Ultrasound (IVUS) and Optical Coherence Tomography (OCT) Capabilities

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ConaviTM Medical Inc. (www.conavi.com)
is pleased to announce the first clinical use of the NovasightTM
Hybrid System, which enables simultaneous imaging of coronary arteries
with both intravascular ultrasound (IVUS) and Optical Coherence
Tomography (OCT). IVUS or OCT are typically used by interventional
cardiologists to image coronary anatomy during minimally invasive
procedures, such as angiograms, angioplasty and stenting procedures.
Drs. Tej Sheth and Natalia Pinilla Echeverri are co-investigators at
Hamilton General Hospital where the procedures were performed under a
Health Canada Investigational Testing Authorization. The technology
originated from Dr. Courtney's laboratory at Sunnybrook Research
Institute in Toronto and is being commercialized by Conavi Medical.

"The purported advantages of the synergistic information that IVUS and
OCT can provide have been highly anticipated in the interventional
cardiology community," says Dr. Brian Courtney, President and CEO of
Conavi. "These cases performed in Hamilton represent the first worldwide
clinical use of any system that combines IVUS with OCT on a single
catheter. In an era of personalized and precision medicine, we believe
that the ability to collect comprehensive imaging data in patients with
coronary artery disease (CAD) provides an important opportunity to
generate improved clinical decision-making capabilities for these
patients in the future."

"The Novasight Hybrid imaging catheter is a deliverable imaging system
that is able to rapidly and simultaneously acquire co-registered IVUS
and OCT images," says Dr. Sheth. "In this study, we are collecting the
first human images with this novel imaging system to confirm the
functionality of the technology in the clinical environment and to help
inform future studies. We have been able to identify some early examples
of the synergies between these two modalities in our clinical experience
so far. Ultimately, hybrid IVUS/OCT imaging has the potential to
overcome the limitations of IVUS or OCT alone in accurately
characterizing atherosclerotic tissue and in guiding coronary
interventions."

About Conavi Medical:

Conavi Medical Inc., is a privately-held Canadian company focused on
designing, manufacturing, and selling imaging technologies to guide
minimally invasive cardiovascular procedures. For more information,
visit http://www.conavi.com/.

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