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Burt's Bees Nature-Based Sensitive Skin Care Clinical Results Published in Journal of Drugs in Dermatology

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Nature-based regimen delivers improved skin health vs.
dermatologist-recommended synthetic regimen

Burt's Bees®, a leading provider of personal care products
committed to natural health and beauty solutions, today announced that
the Journal of Drugs in Dermatology (JDD) published clinical data
supporting the efficacy of Burt's Bees nature-based sensitive skin
regimen at maintaining healthy skin barrier function.

This press release features multimedia. View the full release here:
https://www.businesswire.com/news/home/20180813005082/en/

Burt's Bees Sensitive Skin (Photo: Business Wire)

Burt's Bees Sensitive Skin (Photo: Business Wire)

Burt's Bees' nature-based regimen, consisting of Sensitive Facial
Cleanser, Sensitive Daily Moisturizing Cream and Sensitive Night Cream,
was shown to be well-tolerated, as well as clinically, and
statistically, superior to the control, a leading
dermatologist-recommended synthetic regimen.

"The data suggest that nature-based products can be effective for
patients who seek alternatives to conventional, synthetic skin care
products," said Zoe Draelos, MD, Dermatology Consulting Services, High
Point, NC, the study's principal investigator. "Patients with sensitive
skin saw a clinical improvement in overall skin appearance, specifically
in visual and tactile smoothness, clarity, and radiance."

This 4-week, double-blind, randomized study was conducted in 120 women
with sensitive skin who suffer from clinically diagnosed rosacea, atopic
dermatitis/eczema, or cosmetic intolerance. Results demonstrated that
Burt's Bees Sensitive Skin Regimen clinically and statistically improved
physician-rated overall skin appearance by 34% with similar improvements
in visual and tactile smoothness, clarity and radiance. In contrast, the
maximum improvement in women using the synthetic regimen was 4%.

No clinically significant tolerability issues were reported in either
regimen after 4 weeks of daily administration. Both regimens improved
epidermal barrier function as measured by transepidermal water loss. The
Burt's Bees regimen optimized skin hydration to improve and maintain
skin health. The synthetic regimen was associated with over hydration
possibly resulting from the occlusive barrier it provides.

"These data support the efficacy of nature-based formulations on
sensitive skin, as well as the benefit of homeostasis of the epidermal
barrier for overall skin health, including maintaining appropriate
levels of hydration and allowing skin to breathe," said Hemali Gunt,
PhD, Head of Clinical and Scientific Affairs, at Burt's Bees. "This
publication affirms the benefit of natural products for sensitive skin,
and offers an effective option as more people seek natural alternatives
to conventional formulas."

Read the full-text article in the JDD August 2018 issue: http://jddonline.com/articles/dermatology/S1545961618P0908X/1

About the Study: A participant- and investigator –blinded,
controlled product, single site study was performed in an outpatient
setting on one hundred and twenty female subjects, 19-60 years old, with
Fitzpatrick skin types I-V. All subjects were diagnosed with either:
eczema/atopic dermatitis, rosacea, or cosmetic intolerance syndrome. The
evaluation was performed at baseline, 2 and 4 weeks of twice daily
randomized treatment with Burt's Bees Skin Care Regimen or a leading
conventional skin care brand regimen. The Burt's Bees Skin Care Regimen
included Burt's Bees Sensitive Facial Cleanser (used day and night),
Burt's Bees Sensitive Daily Moisturizing Cream (used in the day) and
Burt's Bees Sensitive Night Cream (used at night). The Control Skin Care
Regimen included a leading conventional brand Skin Cleanser (used day
and night) and a leading conventional brand Moisturizing Lotion (used
day and night).

The peer review article is entitled: "Evaluation of the Performance
of a Nature-Based Sensitive Skin Regimen in Subjects with Clinically
Diagnosed Sensitive Skin" [Draelos ZD, Levy SB, Lutario C, Gunt H. J
Drugs Dermatol. 2018; 17(8): 611-616].

Burt's Bees® has been offering distinctive earth-friendly,
natural health and beauty care products for over 30 years. From a
beekeeper's backyard in Maine to the leading edge of natural, Burt's
Bees knows natural solutions for beauty from the inside out and operates
with The Greater Good™ top of mind. www.burtsbees.com
NYSE: CLX CLX-B

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