Market Overview

NexGen Medical Systems, Inc. Launches XCOIL® Large Vessel (18mm) Thrombectomy System

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Limited Market Release expands the utility of the XCOIL®
for Deep Vein Thrombosis

NexGen Medical Systems, Inc., a Minneapolis medical device company,
announced today the successful completion of the first human use of
their XCOIL® Large Vessel (18mm) Thrombectomy System for the
treatment of deep vein thrombosis (DVT). The new device, an expansion of
the successful XCOIL® 12mm System, is designed to rapidly
remove blood clots in large vessels, such as the iliac vein.

The XCOIL® Thrombectomy Systems are comprised of an
Encapsulator sheath and a Retractor catheter. The Retractor is used to
engage and extract the clot, pull it into the Encapsulator and remove
the clot from the body, while minimizing the need for clot-dissolving
lytic drugs.

"This expansion of the XCOIL® platform provides our customers
with an effective portfolio of solutions for the many patients suffering
from deep vein thrombosis in the United States," said Denis Harrington,
President and Chief Executive Officer of NexGen Medical Systems. "With
the successful addition of our Large Vessel solution, NexGen Medical
continues to demonstrate our commitment to developing advanced solutions
for treating DVT blood clots and in the future expanding our platforms
to treat pulmonary embolism clots."

Dr. David Buechner, MD FSIR, Methodist Hospital, Memphis TN, shared,
"Our therapeutic goal is to rapidly restore blood flow by removing the
clot, quickly and safely, while minimizing the need for clot-dissolving
drugs which are not appropriate for all patients and can have negative
side effects. The XCOIL® Thrombectomy System provides a rapid
mechanical solution and may improve outcomes, and reduce costs, for our
patients."

Blood clots can cause serious diseases and disorders, including deep
vein thrombosis (leg clots), pulmonary embolisms and strokes. DVT occurs
when a blood clot forms in the deep veins of the body, typically the
legs. Blood clots account for more deaths each year than breast cancer,
road traffic accidents, and AIDS combined.

About NexGen Medical Systems, Inc.
NexGen Medical Systems,
Inc. is a privately held U.S. company that designs, produces and markets
next-generation devices for the rapid removal of disease-causing blood
clots from veins and arteries. For more information on the company and
its products, please visit www.xcoil.com

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