Market Overview

Cell Medica Appoints New CEO to Drive CAR and TCR Clinical Development and Commercialisation


Cell Medica (or ‘the Company'), a leader in the development, manufacture
and marketing of personalised cellular immunotherapeutics for the
treatment of cancer, has appointed Chris Nowers as Chief Executive
Officer and Executive Director. His appointment follows founder Gregg
Sando's decision to step down as Chief Executive Officer and Director of
the Company and is effective 1 August 2018.

Mr Nowers joins Cell Medica from the cancer immunotherapy company Kite
Pharma (Kite), where he was Head of Europe and responsible for the full
commercialisation of the CAR-T therapy axicabtagene ciloleucel. At Kite
he built the European organisation from the ground up and, post the $12
Bn acquisition by Gilead Sciences in 2017, was subsequently responsible
for the continued expansion of the Kite organisation within the Europe,
Middle East and Africa structure. Previous to his role at Kite, he has
had a career spanning more than 25 years in the biopharma industry. He
has held a number of senior leadership roles that included CEO of
Avantogen Oncology, General Management roles at Amgen, and senior global
and regional commercial leadership roles at Bristol-Myers Squibb (BMS).
Whilst at BMS, he built and led teams that delivered the successful
launches of the checkpoint inhibitors ipilimumab and nivolumab.

Mr Sando, a pioneer in the field of cellular immunotherapy, established
Cell Medica in 2006 and led the company's transition into the CAR-T
technology space. The upcoming initiation of clinical trials
investigating CAR-modified cell therapy products will mark an important
new chapter in the Company's development. He will assist over the coming
months in transitioning to new senior leadership.

Annalisa Jenkins, Chair of Cell Medica, commented:
would like to thank Gregg for his vision and commitment over the last 12
years, which has led to Cell Medica becoming a leader in cellular
immunotherapy for cancer. He has built an experienced international team
with the capability to build on existing research partnerships and
develop the internal pipeline to maximise shareholder value.

"We are pleased to welcome Chris as Cell Medica's new CEO. His
experience in the commercialisation of oncology programmes is an
excellent fit for the Company's ambitions as we progress towards
realising our goals of delivering compelling new cellular
immunotherapies for the treatment of cancer patients."

Gregg Sando commented:
"It has been a great
experience founding Cell Medica and leading a team of dedicated
colleagues and research collaborators who have been working together to
transform the treatment of cancer through cell-based immunotherapy. The
Company is well positioned for an exciting future and it is now time to
transition to new leadership who will take our products and technology
through clinical development and commercialisation. My thanks and
appreciation to the extended Cell Medica team and partners, past and

Chris Nowers commented:
"Cell Medica has an
exciting array of technologies that will help unlock the potential of
personalised cellular immunotherapies for both blood cancers and solid
tumours. I look forward to working with the Company's talented executive
and scientific teams to take these promising treatments to patients
through clinical development."

- ENDS -

Notes to Editors

About Cell Medica
Cell Medica is committed to transforming
patients' lives through developing the significant therapeutic potential
of cellular immunotherapy for the treatment of cancer. We are advancing
innovative cell-based therapies using proprietary technology platforms
incorporating chimeric antigen receptors (CARs) and engineered T cell
receptors (TCRs). Our CAR-modified T cell products are being developed
in collaboration with Baylor College of Medicine and University of North
Carolina. Cell Medica's differentiated approach utilises NKT cells (a
subset of T cells) engineered to express IL-15 to maintain anti-cancer
potency within the immunosuppressive tumour micro-environment. We are
developing both autologous and allogeneic (off-the-shelf) products using
the CAR-NKT cell technology. In the field of engineered TCRs, we are
working with University College London, to develop the Dominant TCR
technology to improve the potency of TCR-modified T cells while
maintaining the safety profile. Our product portfolio also includes
baltaleucel-T (EBV-specific T cells) for the treatment of lymphomas
associated with the Epstein Barr virus. Cell Medica is headquartered in
London with subsidiaries in Zurich and Houston.

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