Market Overview

Global Bone Graft Substitutes Markets to 2024: Annual Estimates & Forecasts - Focus on Key Players


Global Bone Graft Substitutes Markets to 2024: Annual Estimates & Forecasts - Focus on Key Players

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DUBLIN, July 23, 2018 /PRNewswire/ --

The "Bone Graft Substitutes - Global Strategic Business Report" report has been added to's offering.

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The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World. Annual estimates and forecasts are provided for the period 2016 through 2024. Also, a five-year historic analysis is provided for these markets. This report analyzes the worldwide markets for Bone Graft Substitutes in US$ Million.

The US market is additionally analyzed by the following Segments:

  • Demineralized Bone Matrix
  • Bone Morphogenetic Protein
  • Stem Cell Based Bone Grafts
  • Synthetic Bone Grafts

The report profiles 42 companies including many key and niche players such as:

  • AlloSource (USA)
  • Baxter International, Inc. (USA)
  • DePuy Synthes Companies (USA)
  • Exactech, Inc. (USA)
  • SeaSpine Holdings Corporation (USA)
  • LifeNet Health, Inc. (USA)
  • Medtronic plc (Ireland)
  • NovaBone Products LLC (USA)
  • NuVasive, Inc. (USA)
  • Orthofix International N V (Curaao)
  • RTI Surgical, Inc. (USA)
  • Smith & Nephew Plc (UK)
  • Stryker Corporation (USA)
  • Wright Medical Group N.V. (Netherlands)
  • Xtant Medical Holdings, Inc. (USA)
  • Zimmer Biomet Holdings, Inc. (USA)

Key Topics Covered:


Bone Grafts - A Prelude
Developing Markets Hold Lucrative Potential for Bone Graft Substitutes
Rise in Volume of Orthopedic Procedures Boosts Prospects
Bone Grafting - An Important Procedure for Healing Fractures
What Drives Physicians' Choice of Bone Grafts?
Challenges for Different Bone Grafts
Patient Safety Emerges as a Top Priority
Unmet Clinical Needs to Foster R&D Engine
Advanced Allografts Encroach the Use of Autografts in Surgical Procedures
Rise in Popularity of Synthetic Bone Graft Substitutes
Bone Morphogenetic Protein - Safety Concerns Impact Growth Prospects
Stem Cell Based Bone Grafts: Promising Growth Ahead
DBM: Strong Growth but Tough Competition
Demineralized Bone Matrix (DBM) Allografts Offered by Select Companies

A Review of Major Factors Affecting Growth
Increasing Incidence of Degenerative Intervertebral Disc Diseases
Rising Prevalence of Arthritis and Other Orthopedic Disorders
Growing Number of Revision Orthopedic Surgeries
Rise in Spinal Fusions in Private Healthcare
Foot and Extremity Reconstruction - Promising Market for Bone Grafts
Spine Fusion - The Largest Application Market for Bone Graft Substitutes
Dental Bone Grafting - A High Potential Market
Adoption of Dental Implants - Breakdown by Number of Implants in Select Countries
Increasing Visibility of Orthobiological Products to Spur Grafting Options
Technological Advancements Drive Bone Grafts Market
A Glance at Few Recent Innovations/Research Efforts in Bone Grafts
Sea Coral Offers Perfect Biomaterial for Bone Grafts
Indian Scientists at Synthera Develop Innovative Bone Graft Substitutes
NJIT Receives Grant to Commercialize New Bone Graft Substitute Technology
Consortium to Develop SmartBonePep Bio-hybrid Composite Bone Graft
QMUL Researchers Develop Inductigraft Synthetic Bone Grafts
Researchers Develop Aerograft Dental Bone Graft Material for Dental Procedures
Precision Machined Allografts Gain Surgeon Preference
Disease Transmission through Bone Grafts - A Major Safety Concern
Lack of Standards in Bone Graft Substitute Market
Reimbursement Issues Continue to Haunt Bone Grafts Market
Regional Regulations & Religious Beliefs Hamper Bone Graft Substitutes Market
Synthetic Bone Grafts - Solution for Halal Bone Graft Implantation
Bone Glue - A Potential Threat to the Bone Graft Market
Alliances with Organ Procurement Organizations: A Shot in the Arm
Limited Availability of Donor Tissues
Competition Intensifies from Alternative Tissue Repair Therapies
Substitute Technologies Threaten to Replace Spinal Fusions
Bone Grafts Termed as Tissues Suffer From Inconsistent Patient Outcomes
New Ways of Fixing Broken Bones
BoneCure Sleeve - Heading Towards the Human Market
Bioactive Glass - Suitable for Weight Bearing Portion
Review of Demographic Drivers
Aging Population: A Strong Demographic Driver
Rise in Global Obesity Epidemic Boosts Market Growth
Facts & Statistics on the Rising Obesity Levels: Important Opportunity Indicators

Bone Grafts: A Definition
Bone Grafts: A Peek into their Mechanism of Action
Types of Bone Grafts
Scoring of Osteoconduction, Osteoinduction, and Osteogenesis Properties of Bone Grafts by Type
Standard Allografts
Machined Bone Allografts
Demineralized Bone Matrix
Bone Morphogenetic Proteins (BMPs)
Basic Functions of TGF-Beta
Synthetic Bone Grafts
Collagen-based Matrices
Ceramic: A Material of Choice
Hydroxyapatite: A Major Calcium Phosphate Based Ceramic
Calcium Sulfate
Polymer Based Bone Grafts
Coral: A Valuable Synthetic Graft Material
Application of Bone Grafts
Spinal Fusion
Trauma & Reconstructive Surgeries
Reconstructive Surgeries
Joint Revision Arthroplasty
Oral, Periodontal, and Cranio-Maxillofacial
Tissue Recovery & Processing: A Review
Tissue Banks
Tissue Processing
Tissue Distribution
An Illustration of the Tissue Recovering, Processing, & Distribution Network

Regulatory Issues
FDA Classification of Bone Products
Human Cells, Tissues and Cellular and Tissue-Based Products (HCT/Ps)
National Organ Transplant Act (NOTA)
Good Tissue Practices
Tissue Banking Regulation
FDA Regulations on Xenograft
DBM-based Products in US
Synthetic Bone Graft Substitutes

Bone Graft Products of Select Players

6.1 Focus on Select Players

6.2 Product Innovations/Introductions
AlloSource and Stryker Unveil the ProChondrixCR Cryopreserved Osteochondral Allograft
LifeNet Health launches AngioGraft Aortoiliac Artery
Royal Biologics Launches MAXX-FuseLine of Allografts
NovaBone launches NovaBone IRM and IRM MacroPOR Biologically Active Bone Graft Substitutes
Leader Biomedical Group DBM, cleaned with eCOO Clean Technology
Antibe Therapeutics Launches PentOS OI Max for Dental Biologics Market
Zimmer Biomet Introduces PrimaGen Advanced Allograft
Citagenix Launches PentOS OI Putty Bone Graft Substitute
AlloSource Introduces ProChondrix Cartilage Restoration Matrix

6.3 Recent Industry Activity
Bonesupport Enters into Agreement with Collagen Matrix
DePuy Synthes Enters into Agreement with Prosidyan to Promote the FIBERGRAFT Family of Products in the US
Medtronic Receives FDA Approval of Infuse(TM) Bone Graft in New Spine Surgery Indications
Exactech Completes Merger with TPG Capital
Molecular Matrix Receives FDA Clearance for Osteo-PTM Synthetic Bone Graft Substitute
RTI Surgical to Acquire Zyga Technology
SeaSpine Receives FDA 510(k) Clearance for OsteoBallast Demineralized Bone Matrix in Resorbable Mesh
BONESUPPORT Signs Agreement for Bio-Ceramic Bone Substitute Products in the Italian Market
Prosidyan Receives FDA 510(k) Clearance for FIBERGRAFT BG Matrix - Bone Graft Substitute for Postero-lateral Spinal Fusion
DSM Enters into Partnership with Cerapedics to Develop and Manufacture Next Generation of Peptide Enhanced Bone Graft
Artoss Announces Availability of NanoBone Bone Graft Products through DAPA
Bonesupport Enters into Commercialization Agreement for the French Market
BoneSupport Extends Distribution agreement with Zimmer Biomet for Cerament TM Bone Void Filler
Kuros Biosciences Acquires Xpand Biotechnology
AllowSource Receives Patent for ProChondrix Cartilage Restoration Matrix
MiMedx Group Takes Over Stability Biologics



8.1 The United States
A. Market Analysis
US-The Largest Market for Bone Graft Substitutes
Aging Population: A Weighty Demographic Growth Factor
Rising Incidence of Degenerative Intervertebral Disc Diseases
Back Pain
Rise in Revision Orthopedic Surgeries Bodes Well for Bone Graft Substitutes Market
Synthetic Bone Grafts to Drive Growth
Stem Cell Bone Grafts: A Promising Segment in BGS Market
Spinal Surgery Market: Opportunity for Bone Grafts Market
Dental Bone Graft Substitutes Market: An Overview
Orthopedic Biomaterials Market - An Overview
Orthobiologics Market - Overview
Regulatory Challenges Limit Growth in the Bone Graft Substitutes
Competitive Scenario
B. Market Analytics

8.2 Canada
Market Analysis

8.3 Japan
A. Market Analysis
Current and Future Analysis
Dental Bone Graft Substitutes Market
B. Market Analytics

8.4 Europe
A. Market Analysis
European Market for Bone Graft Substitutes: An Overview
Synthetic Bone Graft Drives the BGS Market
Bone Morphogenetic Protein (BMP) Market
Dental Biomaterials Market in Europe: An Insight
B. Market Analytics

8.5 Asia-Pacific
A. Market Analysis
Current and Future Analysis
Dental Bone Graft Substitutes Market in Asia-Pacific - An Overview
Focus on Select Regional Markets
Current and Future Analysis
South Korea
B. Market Analytics

8.6 Latin America
A. Market Analysis
Current and Future Analysis
Dental Bone Graft Substitutes Market
Brazilian Orthopedic Devices Market
B. Market Analytics

8.7 Rest of World
A. Market Analysis
Current and Future Analysis
B. Market Analytics


Total Companies Profiled: 57 (including Divisions/Subsidiaries - 60)

  • The United States (38)
  • Canada (1)
  • Europe (17)
    • France (2)
    • Germany (2)
    • The United Kingdom (4)
    • Rest of Europe (9)
  • Asia-Pacific (Excluding Japan) (3)
  • Africa (1)

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