Market Overview

Waters Bolsters Mass Spectrometry Imaging Portfolio with Acquisition of Prosolia's DESI Technology

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Desorption Electrospray Ionization (DESI) Imaging Technology Enables
Analysis of Spatial Distribution of Molecules in Tissue, and thus Deeper
Biological Insights.

Today, Waters Corporation (NYSE:WAT), Prosolia, Inc. and the Purdue
Research Foundation (PRF) announced that Waters® acquired
exclusive rights to Desorption
Electrospray Ionization (DESI) technology
for all mass spectrometry
applications from Prosolia and PRF.

This press release features multimedia. View the full release here:
https://www.businesswire.com/news/home/20180723005340/en/

Waters SYNAPT G2-Si High Definition Mass Spectrometer with DESI Source (Photo: Business Wire)

Waters SYNAPT G2-Si High Definition Mass Spectrometer with DESI Source (Photo: Business Wire)

"The acquisition of DESI technology bolsters Waters' portfolio of mass
spectrometry imaging innovations, a rapidly expanding MS technique for
biomedical research and related applications," said Chris O'Connell,
Chairman and Chief Executive Officer, Waters Corporation. "DESI mass
spectrometry imaging provides complementary and actionable data when
compared to classical histopathology imaging technologies with major
advantages in analyzing the molecular fingerprint within a sample, thus
delivering deeper biological insights. Ultimately, these insights will
lead to better understanding of disease and enable the development of
new, more effective medical therapies."

DESI imaging technology uses a charged jet of solvent depositing
micro-droplets onto a sample's surface where analytes are desorbed into
a gas phase at ambient pressure and temperature. Subsequently, they are
drawn in and analyzed by mass spectrometry.

"We at Prosolia are proud of our role in developing and commercializing
DESI technology," said Justin Wiseman, Chief Executive Officer,
Prosolia. "The potential for MSI analysis using DESI technology is
significant because of the quality of the data, the minimal sample
preparation required, and the non-destructive nature of the technique
allowing for multimodal analysis on a single sample."

In connection with Waters' acquisition of DESI intellectual property
from Prosolia and licensing from PRF, Waters and Purdue University,
where DESI was invented by a team led by R. Graham Cooks, the Henry Bohn
Hass Distinguished Professor of Chemistry, have also established a
relationship under the terms of a new license agreement. Accordingly,
Waters will provide Purdue University with a Synapt™
G2-Si
time-of-flight mass spectrometer to continue to
advance research applications of DESI technology.

"Today's announcement is an important milestone in the continued growth
of DESI to the benefit of scientists around the globe. We congratulate
Justin and the Prosolia team for their accomplishments and look forward
to collaborating with Waters as it takes DESI into the future,"
commented Dr. Cooks.

Waters will continue to support its customers who are already realizing
the benefits of DESI technology with their Xevo™ and Synapt
time-of-flight mass spectrometers. As the technology transitions from
Prosolia to Waters, Prosolia will also continue supply DESI technology
for certain non-Waters mass spectrometer configurations until September
30, 2019. Prosolia will be responsible for and will continue to honor
its warranty commitments made prior to Waters' acquisition of the DESI
technology to those scientists and organizations who currently have a
DESI source unit on any non-Waters mass spectrometer. More details can
be found at Prosolia's website - https://prosolia.com/.

About Waters

Waters Corporation (NYSE:WAT), the world's leading specialty
measurement company, has pioneered chromatography, mass spectrometry and
thermal analysis innovations serving the life, materials and food
sciences for nearly 60 years. With approximately 7,000 employees
worldwide, Waters operates directly in 27 countries, including 11
manufacturing facilities, and with products available in more than 100
countries.

Waters is a registered trademark of the Waters Corporation.

About Prosolia

Prosolia, Inc. is a privately-held scientific instruments company
engaged in the development and marketing of analytical tools that
enhance and expand the use of mass spectrometers. Our portfolio of
scientific tools includes innovative sample introduction and surface
analysis systems with intuitive software, and all of which are part of
workflows that reduce complexity and deliver faster time-to-results.
Guided by the vision of democratizing the mass spectrometer, Prosolia is
making the power of its measurements more accessible to scientists,
clinicians and technicians. Our Desorption Electrospray Ionization
(DESI) technology paved the way to achieving this vision with its
invention in 2004 by a team led by Prof. R. Graham Cooks of Purdue
University and included Dr. Zoltan Takats, a scientific founder, and
Justin Wiseman, Prosolia's Chairman, President & CEO.

About Purdue Research Foundation

The Purdue
Research Foundation
is a private, nonprofit foundation created to
advance the mission of Purdue University. Established in 1930, the
foundation accepts gifts; administers trusts; funds scholarships and
grants; acquires property; protects Purdue's intellectual property; and
promotes entrepreneurial activities on behalf of Purdue. The foundation
manages the Purdue Foundry, Purdue Office of Technology
Commercialization, Purdue Research Park and Purdue Technology Centers.
The foundation received the 2016 Innovation and Economic Prosperity
Universities Award for Innovation from the Association of Public and
Land-grant Universities. For more information about funding and
investment opportunities in startups based on a Purdue innovation,
contact the Purdue Foundry at foundry@prf.org.

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