Market Overview

Stroke Awareness Month News: First of Its Kind Technology Reduces Stroke by More Than 60 Percent in Patients Undergoing Common Heart Procedure


Strokes are unpredictable and devastating; people with a high surgical
risk for stroke may never have one, while those with a low risk can
suffer a stroke without warning. A new technology cleared by the FDA and
introduced just a year ago has proven that it can reduce the incidence
of stroke by more than 60 percent when used during an increasingly
common heart procedure, transcatheter aortic valve replacement, known as
TAVR. Since then, Protected TAVR with the Sentinel
Cerebral Protection System
is now used by more than 10 percent of
TAVR centers nationwide, including many of the leading heart and stroke
centers in the country, such as Cedars-Sinai, Cleveland Clinic, New
York-Presbyterian Hospital and Kaleida Health at Buffalo General.

During Stroke Awareness Month in the month of May, it is important for
patients suffering from severe aortic stenosis who are considering TAVR
to be aware that there is technology available to make their treatment
safer and offer them peace of mind, if they are concerned about the risk
of stroke. The Sentinel Cerebral Protection System protects patients by
filtering, capturing and removing pieces of tissue, calcium and other
harmful debris released during TAVR before it can reach the brain and
cause a blockage, potentially leading to a stroke. Studies have shown
that the Sentinel technology captures debris in 99 percent of patients
undergoing TAVR and has no safety risks associated with it.

Sentinel patient Jim McCutchon of Corpus Christi, Texas said, "Having
aortic stenosis is like flirting with sudden death. My aortic valve was
closing down slowly, and I had to stop to catch my breath even with no
greater exercise than a leisurely walk. I needed TAVR, but I was
concerned that I would have a stroke if I had TAVR without cerebral
protection. I struggled with a three year wait until Sentinel was
available, and then I felt confident to move forward with the procedure.
I've seen pictures of the debris that Sentinel captured on the way to my
brain, and I am thankful that I waited. Since then, I have had no
problems, and I can run and play again."

Minimally-invasive Sentinel technology has been used to safeguard more
than 7,500 patients worldwide and is the most-studied device in the
field of TAVR cerebral protection.

"We would never drive a car without a seatbelt and we should never do
TAVR without embolic protection," said leading TAVR physician Susheel
Kodali, MD, from New York-Presbyterian Hospital.

"Stroke destroys lives, and it is important that we as physicians do all
we can to prevent it. With this in mind, we now use Sentinel technology
in all our TAVR cases and have been able to provide greater brain
protection to patients," said TAVR expert Samir Kapadia, MD, with the
Cleveland Clinic.

About Claret Medical

A privately-held company, Claret Medical develops innovative solutions
for cerebral protection during structural heart and vascular
interventions. Believing that not all cerebral protection devices are
created equal, the company developed the Sentinel dual-filter system as
the only system to capture and remove debris from the patient. It has
been the leader in the field of cerebral protection since 2011 and is
currently the only commercialized cerebral protection device available
in the U.S., Europe and Asia. For more information on Sentinel or the
Company, please visit

View Comments and Join the Discussion!