Market Overview

ACIST Medical Systems Announces Approval and Launch of Next-Generation FFR System


ACIST RXi® Mini™ System Seamlessly Integrates with Cath Lab
Hemodynamic System and FFR Software

ACIST Medical Systems, Inc., a Bracco Group Company, today announced the
global launch of its ACIST RXi® Mini™ System, the next generation system
of its RXi Rapid Exchange FFR System. The RXi Mini System will debut at
the 29th Transcatheter Cardiovascular Therapeutics (TCT) scientific
symposium in Denver, Colorado.

The RXi Mini is designed to provide fractional flow reserve (FFR)
measurements to complement angiography, provide qualitative assessment
of lesion severity, and inform intervention strategy in both diagnosis
and treatment of coronary and peripheral artery disease. The system is
designed to seamlessly integrate with existing hemodynamic systems and
FFR software. The RXi Mini offers flexible mounting configurations, a
simple and intuitive user interface, and a small and unobtrusive system
profile that adapts to your existing workflow and maximizes procedural

The first case in the United States and the world was performed by Dr.
Michael Lim, MD and Director of Cardiology at St. Louis University in
St. Louis, Missouri. During a complex case performed by Dr. Lim, the RXi
Mini System was utilized to measure FFR multiple times during the
procedure. Dr. Lim noted "ACIST has raised the bar in making physiology
accessible and easy to use in the cath lab setting." The small RXi Mini
system is about the size of a fist and connects into hospital
hemodynamic systems where the measurements can be taken and recorded by
lab staff, making the procedure go more smoothly and quickly. "FFR is
the gold standard in diagnosing which lesions will most likely benefit
from coronary interventions, including stent placement. The ACIST Rapid
FFR Mini RXi system makes it much simpler to perform FFR, whenever it is
called for. With this advance, it continues to become easier to guide
treatment decisions by invasive physiologic measurement – there really
aren't that many excuses left for the interventionalist to skip this

Unlike standard pressure wires, the ACIST RXi Mini System and Navvus®
Rapid Exchange FFR MicroCatheter, allows physicians to use their 0.014"
guide wire of choice throughout the procedure, addressing challenges of
pressure wires, including accessibility in challenging anatomies,
maintaining wire position, pressure‐measurement drift and ease of
obtaining post‐intervention FFR.

"ACIST is excited about the additional value and flexibility that the
RXi Mini will provide the cath lab," said Brad Fox, President and CEO,
ACIST Medical Systems, Inc. "This next generation FFR solution reflects
our continued organizational commitment to providing technologies that
simplify procedures and help physicians improve patient care."

ACIST Medical Systems, Inc. is a pioneering
interventional and diagnostic technology company with a portfolio of
advanced products, including the world's first Rapid Exchange FFR and
High Definition IVUS systems. It is also a global market leader in
advanced contrast imaging systems for cardiovascular angiography and
radiology imaging. Through these products, ACIST is demonstrating its
commitment to bringing unique and innovative technologies that simplify
cardiovascular procedures and empower clinicians to treat patients with
superior care. As part of the Bracco Group, ACIST benefits from the
resources of a multinational conglomerate with broad expertise in cath
lab technology and a dedication to continuous advancement. Headquartered
in Eden Prairie, Minnesota, USA, ACIST has worldwide presence with over
300 direct employees and facilities in Silicon Valley, Heerlen, and
Tokyo. To learn more about ACIST, visit

Bracco Group
Bracco has headquarters in Milan, Italy, and
was founded in 1927. It is active in the healthcare sector through
Bracco Imaging (diagnostic imaging), ACIST Medical Systems and HLT
(cardiology) and the Centro Diagnostico Italiano diagnostic clinic. It
has around 3,400 employees and annual total consolidated revenues of
over 1.3 billion Euro. Bracco operates in more than 100 countries
worldwide. To learn more about Bracco Group, visit

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