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Research and Markets: Cellular Imaging Techniques for Neuroscience and Beyond


Research and Markets ( has announced the addition of Elsevier Science and Technology's new book "Cellular Imaging Techniques for Neuroscience and Beyond" to their offering.

The imaging of small cellular components requires powerful instruments, and an entire family of equipment and techniques based on the confocal principle has been developed over the past 30 years. Such methods are commonly used by neuroscience researchers, but the majority of these users do not have a microscopy or a cell biology backgrounds and do can encounter difficulties in obtaining and interpreting results.

This volume brings experts in high-resolution optical microscopy applications in neuroscience and cell biology together to document the state of the art. Outlining what is currently possible, the volume also discusses promising developments for the future and aids readers in selecting the most scientifically meaningful approach to solve their questions. Each chapter discusses instrumentation and technology in relationship to application in research. All of the common and cutting edge trends are covered - fluorescence / laser electron / nonlinear microscopy, infrared fluorescence, multiphoton imaging, tomography, FRAP, live imaging, STED, PALM/STORM, etc.

Key Features

- Single and multiphoton confocal microscopy, and 4-pi confocal microscopy

- Obtaining nanoresolution via photoactivation localization microscopy (PALM)

- Several procedures that correlate observations in optical fluorescence microscopy and electron microscopy

- Study of morphology and function via high-resolution fluorescence procedures

- Additional high-resolution microscopic techniques

Key Topics Covered:

1. Confocal laser scanning: Of instrument, computer processing, and men

2. Beyond Abbe's resolution barrier: STED microscopy

3. Enhancement of optical resolution by 4pi single and multiphoton confocal fluorescence microscopy

4. Nano resolution optical imaging through localization microscopy

5. Optical investigation of brain networks using structured illumination

6. Multiphoton microscopy advances toward super resolution

7. The cell at molecular resolution: Principles and applications of cryo-electron tomography

8. Cellular-level optical biopsy using full-field optical coherence microscopy

9. Retroviral labeling and imaging of newborn neurons in the adult brain

10. Study of myelin sheaths by CARS microscopy

11. High-resolution approaches to studying presynaptic vesicle dynamics using variants of FRAP and electron microscopy


Wouterlood, Floris G.

For more information visit

Source: Elsevier Science and Technology

Research and Markets
Laura Wood, Senior Manager.
U.S. Fax: 646-607-1907
Fax (outside U.S.): +353-1-481-1716
Sector: Healthcare and Medical Devices

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