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T-Cells to Produce Less Toxic Modality in Treatment of Mesothelioma, According to Surviving Mesothelioma


According to Surviving Mesothelioma, research shows that T-Cells are being studied for their effectiveness in treating mesothelioma.

Raleigh, NC (PRWEB) October 30, 2012

When it comes to predicting which patients will benefit the most from a combination of chemotherapy and immunotherapy, a team of British researchers is encouraging doctors to read the T-cells.

How do T-Cells work?

T-cells are part of the immune system and can be used as an indicator of its health. In the new British study, 40 mesothelioma and lung cancer patients who underwent platinum-based chemotherapy saw a dramatic drop in all types of T-cells. The most profound effect was seen in the regulatory T-cells (Treg) that are responsible for maintaining balance in the immune system. Patients whose CD8(+) T-cells recovered quickly after chemotherapy had the greatest overall survival.

What do the studies show for mesothelioma patients?

In an article in the British Journal of Cancer, the study's authors conclude “Chemotherapy potentially provides a favourable environment for the development of anti-tumour immunity through transient Treg depletion and regeneration of the T-cell pool”. They also suggest that measuring the level of CD8(+) T-cells in particular could serve as a useful prognostic indicator for mesothelioma patients undergoing platinum-based chemotherapy.

In the end, it is hoped that the research being done on immune therapy and T-Cells will prove to be an effective means for treating the two main types of mesothelioma: pleural mesothelioma and peritoneal mesothelioma, both caused by exposure to asbestos.

About Surviving Mesothelioma:

Surviving Mesothelioma is a website dedicated to providing information, news, and resources for mesothelioma patients and their loved ones. Supported by the Cancer Monthly organization, Surviving Mesothelioma reports on the latest news regarding mesothelioma treatments, information about finding mesothelioma doctors, treatment results, and books and testimonials from mesothelioma patients and survivors.


The information in this article is for educational and informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read in this article. This article was written by a third party and its content reflects the views of the third party and does not necessarily reflect the views or opinions or of Surviving Mesothelioma or Cancer Monthly.

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