Premier's ProvideGx™ Program to Supply Sodium Bicarbonate Injection to Providers

Premier Inc. PINC, through its ProvideGx™ program, has partnered with Exela Pharma Sciences, LLC, to supply sodium bicarbonate injection to healthcare providers, a drug that has been in shortage in the U.S. for nearly two years.

Sodium bicarbonate injection is most commonly used for urgent treatment of cardiac emergencies, such as cardiac arrest, heart attacks, strokes and other life-threatening emergencies. The product is also used to treat excessive acid or potassium in the blood stream, dehydration and certain drug overdoses. Limited supplies of the drug today are being imported from Australia under special U.S. Food and Drug Administration (FDA) rules that apply in shortages, but the costs for the imported product are 300 percent higher than the U.S. alternatives.

Exela Pharma Sciences is a new producer of sodium bicarbonate, having just received approval for its Abbreviated New Drug Application (ANDA) from the FDA to begin manufacturing. As such, they will be an entirely new source of supply, helping fulfill the increased demand needs that today's incumbents are unable to accommodate.

"Medical grade, injectable versions of sodium bicarbonate are in dire shortage, compromising the care provided to patients with kidney conditions, diabetes complications and cardiac emergencies," said Premier's President, Michael J. Alkire. "Our members have told us that this is one of the most urgently needed drugs in the emergency room, and we are proud to partner with Exela Pharma Sciences to introduce a new supplier to the market in an effort to end this life-threatening shortage once and for all."

"For many patients there are few therapeutic alternatives to sodium bicarbonate," said Randy Ball, MBA, RPh, FASHP, Vice President and System Pharmacy Officer at Texas Health Resources. "For the better part of two years, we've been conserving our supplies to make sure we have this important medication for those patients who need it. Having a continuous, reliable supply of this critical drug will take a lot of pressure off our clinicians and allow them to provide it to all patients who would benefit from its use. We are hopeful that Premier's winning strategy for solving drug shortages will incent other organizations to put patients first and raise the bar across American healthcare."

The ProvideGx program identifies safe, high-quality supply sources for drugs that are or may be at risk of being added to the national drug shortage list. Guided by health systems with more than 1,000 hospitals across the nation, Premier's ProvideGx program has directly led to the reliable supply of seven other critical shortage drugs in 2019 alone, including metoprolol, cystine hydrochloride, diphenhydramine, hydromorphone, lidocaine, morphine and thiamine, with plans to introduce additional drugs from a target list of more than 60 products in months to come.

ProvideGx is part of Premier's ongoing effort to help facilitate the availability of hundreds of high-quality products, including drugs for which there may be supply challenges. In doing so, Premier is insulating its members from supply fluctuations that may affect the market at large.

After a period of decline, drug shortages in America increased significantly in 2018, with an estimated 124 drugs currently at risk or not readily available for U.S. hospitals, according to the FDA's drug shortage list. With wide-ranging effects on patient care, drug shortages can add time and expense as providers search for therapeutic alternatives and manage supplies, potentially delaying certain elective hospital procedures.

The financial terms of Premier's agreement for sodium bicarbonate injection were not disclosed. Revenues from this agreement are not expected to materially impact Premier FY 2020 results.

Forward-Looking Statements

Matters discussed in this release that are not statements of historical or current facts, are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements may involve known and unknown risks, uncertainties and other factors that may cause the actual results, performance or achievements of Premier to be materially different from historical results or from any future results or projections expressed or implied by such forward-looking statements. Accordingly, readers should not place undue reliance on any forward-looking statements. In addition to statements that explicitly describe such risks and uncertainties, readers are urged to consider statements in the conditional or future tenses or that include terms such as "believes," "belief," "expects," "estimates," "intends," "anticipates" or "plans" to be uncertain and forward-looking. Forward-looking statements may include comments as to Premier's beliefs and expectations as to future events and trends affecting its business and are necessarily subject to uncertainties, many of which are outside Premier's control. More information on potential factors that could affect Premier's financial results is included from time to time in the "Forward-Looking Statements," "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" sections of Premier's periodic and current filings with the SEC and available on Premier's website at investors.premierinc.com. Forward-looking statements speak only as of the date they are made. Premier undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise that occur after that date.

About Premier Inc.

Premier Inc. PINC is a leading healthcare improvement company, uniting an alliance of more than 4,000 U.S. hospitals and health systems and approximately 165,000 other providers and organizations to transform healthcare. With integrated data and analytics, collaboratives, supply chain solutions, and consulting and other services, Premier enables better care and outcomes at a lower cost. Premier plays a critical role in the rapidly evolving healthcare industry, collaborating with members to co-develop long-term innovations that reinvent and improve the way care is delivered to patients nationwide. Headquartered in Charlotte, N.C., Premier is passionate about transforming American healthcare. Please visit Premier's news and investor sites on www.premierinc.com; as well as Twitter, Facebook, LinkedIn, Instagram and Premier's blog for more information about the company.

View source version on businesswire.com: https://www.businesswire.com/news/home/20190723005312/en/