LAS VEGAS, April 12, 2018 /PRNewswire/ --

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We may have a fresh buy signal brewing in the Biotechnology ETF. Due to the Chinese cooling down a tad with respect to import tariffs, we are seeing a nice up-move in US futures this morning. The biotech ETF now has a very good chance of forming a weekly swing this week. Weekly swings usually mean a hard bottom is in place. IBB printing its lows of the year last Friday the 6th of April when the ETF dropped to $100.52 for the year. As I write, the pre-market price is $104.49. We are long plenty of biotech names in our portfolio. This sector is peculiar in that it can bottom both before and after the S&P500 SPX prints its own respective hard bottoms or intermediate lows. I still maintain the S&P put in its own intermediate low last Monday on the 2nd of April. In all probability, the biotech complex bottomed 4 days after. Therefore let's go through some other reasons why biotech remains a solid investment especially now near its lows for the year.

Some biotechnology stocks active in the sector include: Propanc Biopharma Inc. PPCB, CymaBay Therapeutics, Inc. CBAY, Endocyte, Inc. ECYT, Sorrento Therapeutics, Inc. SRNE, and Celgene Therapeutics CELG.

Propanc Biopharma Inc. PPCB

Market Cap: 1.57M, current share price: $.065 

Propanc Biopharma Inc. (PPCB), a clinical stage biopharmaceutical company focusing on development of new and proprietary treatments for cancer patients suffering from solid tumors such as pancreatic, ovarian and colorectal cancers, this week announced the completion of a scientific advice meeting with te Medicines and Healthcare Products Regulatory Agency (MHRA), UK, regarding the investigational medicinal product (IMP) manufacturing program for PRP, the Company's lead product candidate. A number of topics were raised and clarified regarding the preparation of a clinical trial application (CTA) for a First-In-Human study in the UK. Key topics included the definition of starting material under Good Manufacturing Practice (GMP) principles, as well as certain tests to be conducted as part of the ongoing quality assurance and control requirements for manufacture of a biological product for human use.

CymaBay Therapeutics, Inc. CBAY

Market Cap: $678.82M, current share price: $14.09 

CymaBay Therapeutics, Inc. (CBAY), just announced that a late-breaking poster presentation describing new data from a second interim analysis of its ongoing Phase 2 study of seladelpar in patients with primary biliary cholangitis (PBC) will be featured during The International Liver CongressTM hosted by the European Association for the Study of Liver Diseases (EASL) in Paris, France (April 11-15, 2018).  Seladelpar is an orally administered, potent and selective peroxisome proliferator-activated receptor delta (PPARδ) agonist currently in development for PBC and nonalcoholic steatohepatitis (NASH).

Endocyte Inc. ECYT

Market Cap: $620.74M, current share price: $9.27 

Endocyte, Inc. (ECYT), a biopharmaceutical company developing targeted therapeutics for personalized cancer treatment, announced that four posters will be presented by Endocyte scientists at the American Association for Cancer Research (AACR) Annual Meeting 2018 to be held in Chicago, IL, April 14 - 18, 2018.

The company will present two posters and a late-breaking abstract relating to Endocyte's chimeric antigen receptor T-cell (CAR T) adaptor molecule (CAM) platform, along with a poster on PSMA-617.

Sorrento Therapeutics, Inc. SRNE

Market Cap: $564.37M, current share price: $6.22 

Sorrento Therapeutics, Inc. (SRNE) and Celularity Inc announced today that the companies have started screening patients for its leading CD38 chimeric antigen receptor (CAR) T cell therapy drug development program, following FDA review allowing clinical trial initiation.

Phase 1, Open-Label, Dose-Escalation, Pharmacokinetic, and Pharmacodynamic Study of the Safety and Efficacy of CAR2 Anti-CD38 A2 CAR-T Cells in Patients with Relapsed or Refractory Multiple Myeloma (http://www.clinicaltrials.gov : NCT03464916). IND filing completed. Study cleared for patient enrollment.

Celgene Corporation CELG

Market Cap: $67.24B, current share price: $89.24 

Celgene Corporation (CELG) will host a conference call and live audio webcast on Friday, May 04, 2018 at 9 a.m. ET to discuss first quarter 2018 financial and operational results. The first quarter results will include the financial and operational results of Juno Therapeutics, Inc. following the March 6, 2018 close of the acquisition. The webcast can be accessed from the Investor Relations page at http://www.celgene.com.

Newlink Genetics Corporation  

Market Cap: $154.38, current share price: $4.16 

NewLink Genetics Corporation (NLNK) today announced a review of its clinical programs.  

This morning's announcement by Incyte and Merck on the ECHO-301 trial for patients with advanced melanoma is a disappointing result for the IDO field.  Indoximod, NewLink Genetics' IDO pathway inhibitor, has a differentiated mechanism of action (MOA) which may demonstrate clinical benefit for patients where direct enzymatic inhibitors have not.  In light of Incyte's announcement, however, NewLink is undertaking a review of its clinical programs and will provide an update when it is completed.

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