Gainers

• HOOKIPA Pharma Inc. (NASDAQ:HOOK) rose 41.8% to $1.90 in pre-market trading after the company announced it entered into an amended and restated collaboration and license agreement with Gilead to develop immunotherapies against HIV.
• Upstart Holdings, Inc.  (NASDAQ:UPST) rose 26.2% to $137.69 in pre-market trading after the company reported better-than-expected Q4 results and issued sales guidance above estimates. The company also announced a $400 million buyback.
• Direct Digital Holdings, Inc. (NASDAQ:DRCT) shares rose 11.2% to $2.78 in pre-market trading. The company recently priced its IPO at $5.50 per unit.
• Corsair Gaming, Inc. (NASDAQ:CRSR) rose 9.1% to $23.49 in pre-market trading. Corsair Gaming Incwill replace First Midwest Bancorp in the S&P SmallCap 600 effective prior to the opening of trading on Friday, February 18. 
• ClearPoint Neuro, Inc. (NASDAQ:CLPT) rose 9% to $9.10 in pre-market trading as the company reported a rise in Q4 sales and issued strong sales forecast.
• Alteryx, Inc. (NYSE:AYX) rose 8.5% to $56.70 in pre-market trading after the company reported better-than-expected Q4 EPS results.
• Senmiao Technology Limited (NASDAQ:AIHS) rose 8.3% to $0.3490 in pre-market trading. The company, on Tuesday, reported Q3 results.
• MDJM Ltd (NASDAQ:MDJH) rose 7.5% to $2.73 in pre-market trading after gaining around 5% on Tuesday.
• Seelos Therapeutics, Inc. (NASDAQ:SEEL) rose 7.4% to $1.30 in pre-market trading following a 10% surge on Tuesday.
• Crocs, Inc. (NYSE:CROX) rose 6.7% to $108.00 in pre-market trading.
• Assertio Holdings, Inc. (NASDAQ:ASRT) rose 6.6% to $2.60 in pre-market trading after declining over 4% on Tuesday.
• Team, Inc. (NYSE:TISI) shares rose 5.5% to $1.34 in pre-market trading after surging 45% on Tuesday.

Find out what's going on in today's market and bring any questions you have to Benzinga's PreMarket Prep.

Check this out: ZoomInfo And 3 Other Stocks Sold By Insiders.

Losers

Also check this out: Insiders Buy Around $112M Of 3 Stocks.