Gainers

• Yunhong CTI Ltd. (NASDAQ:CTIB) shares rose 65.7% to $3.91 in pre-market trading after gaining around 9% on Tuesday.
• KBS Fashion Group Limited (NASDAQ:KBSF) shares rose 34.5% to $3.16 in pre-market trading after climbing 8% on Tuesday.
• Dell Technologies Inc. (NYSE:DELL) shares rose 16.6% to $57.16 in pre-market trading. Dell is exploring options for its 81% stake in VMware, including creating a spinoff, the Wall Street Journal reported.
• THL Credit, Inc. (NASDAQ:TCRD) rose 15.4% to $3.37 in pre-market trading after the company announced it will buyback $20 million of its common stock.
• Novan, Inc. (NASDAQ:NOVN) rose 14.5% to $0.6596 in pre-market trading. Novan shares gained 20% on Tuesday after the company announced it was granted a Canadian patent titled 'Nitric Oxide Releasing Pharmaceuticals Compositions.'
• Ocugen, Inc. (NASDAQ:OCGN) rose 14.5% to $0.2910 in pre-market trading after gaining 9% on Tuesday.
• Brainsway Ltd. (NASDAQ:BWAY) rose 10.3% to $6.89 in pre-market trading. BrainsWay announced the launch of a new website to enhance mental health awareness.
• BioCardia, Inc. (NASDAQ:BCDA) rose 10.1% to $2.39 in pre-market trading.
• Jiayin Group Inc. (NASDAQ:JFIN) rose 9.5% to $4.71 in pre-market trading.
• VMware, Inc (NYSE:VMW) rose 9.2% to $163.00 in pre-market trading. Dell is exploring options for its 81% stake in VMware, including creating a spinoff, the Wall Street Journal reported.
• InflaRx N.V. (NASDAQ:IFRX) rose 9.2% to $5.57 in pre-market trading.
• BIO-key International, Inc. (NASDAQ:BKYI) shares rose 9% to $0.85 in pre-market trading. On Tuesday, BIO-key extended the deployment of biometric authentication solution to West Coast State.
• Viveve Medical, Inc. (NASDAQ:VIVE) rose 8.7% to $0.6528 in pre-market trading.
• Kamada Ltd. (NASDAQ:KMDA) rose 7.7% to $9.63 in pre-market trading after gaining over 7% on Tuesday.
• Seanergy Maritime Holdings Corp. (NASDAQ:SHIP) rose 7.2% to $0.30 in pre-market trading following a 40% surge in the previous session.
• Akers Biosciences, Inc. (NASDAQ:AKER) shares rose 7.1% to $3.75 in pre-market trading.
• Gibraltar Industries, Inc. (NASDAQ:ROCK) rose 6.8% to $50.70 in pre-market trading.

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Check out these big penny stock gainers and losers

Losers

• Castor Maritime Inc. (NASDAQ:CTRM) fell 44.5% to $0.3499 in pre-market trading after the company priced an upsized underwritten public offering of 51,400,000 units at $0.35 per unit.
• Avinger, Inc. (NASDAQ:AVGR) shares fell 25.4% to $0.2910 in pre-market trading as the company priced its $5.4 million underwritten public offering of common stock.
• Fuwei Films (Holdings) Co., Ltd. (NASDAQ:FFHL) fell 14.6% to $5.60 in pre-market trading. Fuwei Films shares jumped 40% on Tuesday after the company reported Q1 results.
• Whiting Petroleum Corporation (NYSE:WLL) shares fell 12.9% to $1.15 in pre-market trading.
• China Rapid Finance Limited (NYSE:XRF) fell 11.5% to $3.08 in pre-market trading after jumping more than 40% on Tuesday.
• Marathon Patent Group, Inc. (NASDAQ:MARA) fell 10.8% to $0.9814 in pre-market trading.
• ESSA Pharma Inc. (NASDAQ:EPIX) fell 9.8% to $5.37 in pre-market trading after gaining over 10% on Tuesday.
• Extraction Oil & Gas, Inc. (NASDAQ:XOG) fell 9.5% to $0.30 in pre-market trading.
• Renewable Energy Group, Inc. (NASDAQ:REGI) fell 9% to $26.00 in pre-market trading after the company cut Q2 adjusted EBITDA guidance.
• L Brands, Inc. (NYSE:LB) fell 7.7% to $13.56 in pre-market trading.
• Micro Focus International plc (NYSE:MFGP) fell 7% to $5.58 in pre-market trading.
• Abraxas Petroleum Corporation (NASDAQ:AXAS) fell 6.5% to $0.29 in pre-market trading following a 7% rise on Tuesday.
• Ideanomics, Inc. (NASDAQ:IDEX) fell 6.4% to $2.80 in pre-market trading. Ideanomics shares dropped over 9% on Tuesday after disclosing a $250 million mixed securities shelf offering.
• TELA Bio Inc (NASDAQ:TELA) fell 6.1% to $20.00 in pre-market trading after the company filed for a 3 million share common stock offering.
• Soleno Therapeutics Inc(NASDAQ:SLNO) fell 6.1% to $1.70 in pre-market trading after the company announced a common stock offering.
• Borr Drilling Limited (NYSE:BORR) fell 6% to $1.28 in pre-market trading after declining 6% on Tuesday.
• Editas Medicine Inc (NASDAQ:EDIT) shares fell 5.7% to $32.39 in pre-market trading after the company priced its 6 million share offering of common stock at $31.25 per share.
• Carnival Plc (NYSE:CUK) fell 5.5% to $14.17 in pre-market trading. S&P lowered Carnival’s credit rating to junk with a negative watch.