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Pfizer Inc. PFE stock was trading slightly higher by 0.4 percent early Wednesday morning after the global pharmaceutical giant announced top-line results from a phase 3 study. The company said the trial of its Tanezumab for the treatment of osteoarthritis pain met all three co-primary endpoints.

Morgan Stanley MS gained nearly 3 percent after reporting its second-quarter results. The banking giant said it earned $1.30 per share in the second quarter on revenue of $10.6 billion versus expectations of $1.11 per share and $10.1 billion.

Catalyst Biosciences Inc CBIO was trading higher by 8 percent although the stock was seen earlier higher by more than 35 percent after reporting encouraging clinical data. The clinical-stage biopharmaceutical company reported positive interim data from a phase 2/3 study of its marzeptacog therapy supports the goal of significantly reducing annualized bleed rates with daily subcutaneous injections of marzeptacog alfa.

Adaptimmune Therapeutics PLC - ADR ADAP gained more than 3 percent after reporting an encouraging update from a study. The T-cell therapy that focuses on treating cancer announced favorable review of safety data from the second dose cohort of patients who received the company's SPEAR T-cells.

Precipio Inc PRPO spiked more than 65 percent after announcing preliminary second-quarter results. The specialty cancer diagnostics company said on a preliminary basis second quarter revenue rose 213 percent from $260,000 a year ago to $815,000.

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