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shares fell 2.67 percent to touch a new 52-week low of $20.79. BMO Capital downgraded Ionis Pharmaceuticals from Outperform to Market Perform.
HollyFrontier CorpHFC shares touched a new 52-week low of $26. HollyFrontier shares have dropped 36.11 percent over the past 52 weeks, while the S&P 500 index has slipped 0.82 percent in the same period.
Alon USA Energy, Inc.ALJ shares reached a new 52-week low of $7.296. Alon USA Energy shares have tumbled 58.08 percent over the past 52 weeks, while the S&P 500 index has declined 0.82 percent in the same period.
Xenon Pharmaceuticals Inc XENE shares dropped 10.10 percent to touch a new 52-week low of $6.09. Xenon Pharmaceuticals shares have dipped 50.87 percent over the past 52 weeks, while the S&P 500 index has dropped 0.82 percent in the same period.
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