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GW Pharmaceuticals PLC- ADR (NASDAQ: GWPH) shares surged 5.37 percent to $70.70 in pre-market trading following the report of Epidiolex data published in The Lancet Neurology.

Sunedison Inc (NYSE: SUNE) shares climbed 4.45 percent to $5.63 in pre-market trading after the company said it has been engaged in discussions relating to a new second lien credit facility of up to $650 million. Adage Capital Partners reported a new stake in SunEdison of 5.37 percent in 13G filing.

Relypsa Inc (NASDAQ: RLYP) shares climbed 3.29 percent to $28.85 in pre-market trading. UK Daily Mail reported a possible $46 per share bid from AstraZeneca plc (ADR) (NYSE: AZN) on Wednesday.

Celgene Corporation (NASDAQ: CELG) shares spiked 0.35 percent to $122.50 in pre-market trading after surging 9.83 percent on Wednesday. Argus reiterated a Buy rating and $155 price target on shares of Celgene.

ARM Holdings plc (ADR) (NASDAQ: ARMH) shares jumped 0.26 percent to $46.47 after gaining 0.94 percent on Wednesday.

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