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Onconova Therapeutics Inc (NASDAQ: ONTX) gained 86.36 percent to $3.69 in pre-market trading after the company reported the submission of investigational new drug application to the FDA for pivotal Phase 3 trial for IV rigosertib in higher-risk myelodysplastic syndromes.

Prima Biomed Ltd. (NASDAQ: PBMD) shares rose 48.01 percent to $1.480 in pre-market trading following announcement of a milestone payment from Novartis AG (ADR) (NYSE: NVS).

Eleven Biotherapeutics Inc (NASDAQ: EBIO) shares climbed 8.40 percent to $5.42 in pre-market trading after surging 22.25 percent on Thursday.

Golden Ocean Group Ltd (NASDAQ: GOGL) shares rose 7.31 percent to $3.67 in pre-market trading after falling 5.26 percent on Thursday.

Nordstrom, Inc. (NYSE: JWN) shares rose 4.71 percent to $78.45 in pre-market trading after the company reported better-than-expected earnings for the second quarter.

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