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Rockwell Medical (NASDAQ: RMTI) shares climbed 14.04% to $10.64. The volume of Rockwell Medical shares traded was 974% higher than normal. The FDA Oncologic Drugs Advisory Committee voted in favor of Rockwell Medical's Triferic 8 to 3.

Sears Holdings (NASDAQ: SHLD) shares moved up 34.13% to $43.82. The volume of Sears Holdings traded was 890% higher than normal. Sears said it is actively exploring REIT transaction involving 200 to 300 owned properties through a rights offering to holdings shareholders.

ChannelAdvisor (NYSE: ECOM) shares rose 44.92% to $17.68. The volume of ChannelAdvisor shares traded was 530% higher than normal. ChannelAdvisor reported upbeat Q3 results.

Q2 Holdings (NYSE: QTWO) surged 23.84% to $18.70. The volume of Q2 Holdings shares traded 524% higher than normal. NAFCU Services has selected Q2 as the preferred partner for mobile and online banking solutions. Stifel Nicolaus raised the price target on Q2 Holdings from $18.00 to $20.00..

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