Benzinga's Top #PreMarket Losers

Insmed

fell 27.21% to $13.32 in pre-market trading after the company reported that Arikayce did not meet pre-specified level for statistical significance. Exelixis

shares dropped 23.45% to $4.93 in pre-market trading after the company issued an update on ongoing COMET-1 phase 3 pivotal trial in men with metastatic castration-resistant prostate cancer. Stifel Nicolaus lowered the price target on the stock from $11.00 to $9.00. International Game Technology

dipped 7.95% to $13.67 in the pre-market session after the company announced its plans to lower 7% of its workforce and cut its earnings guidance for the year. Ballard Power Systems

dipped 5.74% to $5.09 in pre-market trading after jumping 32.19% on Tuesday.