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Benzinga's Top #PreMarket Losers

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INSYS Therapeutics (NASDAQ: INSY) shares fell 19.20% to $36.45 in the pre-market trading after the company received subpoena from Office of Inspector General.

Anadarko Petroleum (NYSE: APC) dipped 10.36% to $75.00. Anadarko disagreed with the Judge's Memorandum of Opinion in Tronox Adversary Proceeding. Citigroup downgraded Anadarko Petroleum from Buy to Neutral and lowered the price target from $108.00 to $86.00.

XOMA (NASDAQ: XOMA) dipped 9.72% to $5.11 in the pre-market session after the company announced a public offering of common stock.

Restoration Hardware Holdings (NYSE: RH) shares dropped 8.23% to $59.90 in pre-market trading after the company announced the resignation of its co-CEO Carlos Alberini. The company reported its adjusted Q3 profit of $0.32 per share, beating analysts' estimates of $0.28 per share.

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