RXi Pharmaceuticals Initiates First Phase 2 Study with RXI-109

RXi Pharmaceuticals Corporation

today announced that the first patient has been enrolled in a Phase 2 study with the anti-scarring product RXI-109. In this study (RXI-109-1301), patients with a long hypertrophic scar in the lower abdominal area are eligible to receive scar revision surgery and subsequent treatment with RXI-109 in one of two treatment regimens.  Patients will receive RXI-109 or placebo on a blinded basis at the distal ends of their revised scar, leaving a central untreated section of the scar. Each patient's revised scar area will provide the opportunity to compare the appearance of the revised areas after treatment with RXI-109 or placebo or when left untreated.  This design allows for intra-subject comparison of the three revised scar segments, as such increasing the power of the study. (Logo:  http://photos.prnewswire.com/prnh/20130917/NE80755LOGO ) "The start of the first Phase 2 clinical study with RXI-109 is a very important step in bringing our first self-delivering (sd-rxRNA®) RNAi closer to the market," said Dr. Geert Cauwenbergh, President and CEO of RXi Pharmaceuticals. He added that, "Not only can the outcome