AVI BioPharma Announces FDA Approval to Proceed With a Modified Dosing of AVI-6003 for Treatment of Marburg Virus

AVI BioPharma, Inc.

, a developer of RNA-based therapeutics, today announced that it has received approval from the Food and Drug Administration (FDA) to proceed with a single oligomer, AVI-7288, in studies in both humans and non-human primates to support the safety and efficacy of post-exposure prophylaxis against Marburg virus infection. AVI-7288 is one of two components that make up AVI-6003. Studies conducted to date have shown that efficacy in non-human primates can be attributed to this single component, while the second component, AVI-7287, does not appear to contribute to efficacy.