Soligenix Unveils Preclinical Data From Filovirus Vaccine Candidates

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  • Soligenix Inc SNGX announced positive preclinical data from its filovirus vaccine candidates, including thermostabilized multivalent vaccines in a single vial platform presentation.
  • Data from non-human primates (NHP) demonstrated efficacy. 
  • Collaborators at the University of Hawaiʻi at Mānoa (UHM) describe the potent efficacy of vaccine candidates protecting against three filoviruses, Zaire ebolavirus, Sudan ebolavirus, and Marburg Marburgvirus.
  • These vaccine candidates contain highly purified protein antigens combined with the novel CoVaccine HT adjuvant in monovalent (single antigen) and bivalent (two antigens) formulations. 
  • Efforts to formulate all three antigens and adjuvant into a thermostable single-vial vaccine platform have been shown to protect 75% of vaccinated NHPs against subsequent Sudan ebolavirus challenge.
  • Price Action: SNGX shares are up 4.79% at $0.94 during the market session on the last check Wednesday.
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