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PsiOxus Therapeutics-Bristol Myers Expand Immuno-Oncology Collaboration

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PsiOxus Therapeutics-Bristol Myers Expand Immuno-Oncology Collaboration
  • PsiOxus Therapeutics Ltd has updated the agreement to advance its clinical collaboration with Bristol-Myers Squibb Co (NYSE: BMY) to evaluate PsiOxus' tumor re-engineering platform, in combination with BMY's Opdivo (nivolumab) to treat a range of tumor types.
  • The first stage of this collaboration combined BMY's Opdivo with PsiOxus' enadenotucirev in Phase 1 SPICE study to evaluate the combination's safety and tolerability and optimize the combination intravenous dosing regimen.
  • The revised collaboration will build upon the initial study data and will combine Opdivo with PsiOxus' NG-641.
  • NG-641 is a tumor re-engineering product using PsiOxus' Tumor-Specific Immuno-Gene Therapy (T-SIGn) platform based upon the enadenotucirev vector.
  • Under the terms of this agreement, PsiOxus will be responsible for conducting the Phase 1 study.
  • Patient recruitment is expected to start in the third quarter of this year.
  • Price Action: BMY shares are up 0.2% at $62.1 in the premarket trading on the last check Wednesday.
 

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