Market Overview

Cowen Starts Uniqure At Outperform, Sees Hemophilia As 'Most Significant' Near-Term Catalyst

Related QURE
Benzinga's Top Upgrades, Downgrades For July 27, 2018
40 Biggest Movers From Yesterday
Related STJ
Abbott Labs Has 'An Emerging Picture Of Top-Tier Growth,' Says Morgan Stanley
Dept. of Homeland Security Provides A Timely Update On Abbott, St. Jude

In a report published Wednesday, Cowen & Co analyst Ritu Baral initiated coverage of Uniqure NV (NASDAQ: QURE) with an Outperform rating, citing the company's "broadly applicable, safe, proprietary baculovirus production AAV5 platform, their promising hemophilia B program and earlier programs."

The company develops gene therapies based on adeno-associated virus (AAV) with a unique insect-cell manufacturing platform that uses insect-specific baculoviruses for vector production. Analyst Ritu Baral pointed out that Uniqure had "rigorous manufacturing standards assuring safety" and had an exclusive license to AAV5 from NIH.

Baral added that AAV5 had "the lowest prevalence of pre-existing antibodies in humans, which allows for a larger treatable patient population and potentially better efficacy."

"Glybera has been approved in the EU for lipoprotein lipase deficiency (LPLD) and has been launched in Germany. A US Ph3 trial is due to start around early 2016," the Cowen & Co report said, while adding, "…we think the Glybera experience has taught QURE how to navigate regulatory requirements, especially in manufacturing and quality control."

Baral believes Uniqure's AAV5 hemophilia B gene therapy is "very promising." Promising data had been released by St. Jude Medical, Inc. (NYSE: STJ). Baral belies that this, along with the low immunogenicity associated with AAV5 "derisks the hemophilia B program, and suggests a superior therapeutic profile to competitors."

Latest Ratings for QURE

Jul 2018Cantor FitzgeraldInitiates Coverage OnOverweight
Jun 2018B. Riley FBRInitiates Coverage OnBuy
May 2018SunTrust Robinson HumphreyInitiates Coverage OnBuy

View More Analyst Ratings for QURE
View the Latest Analyst Ratings

Posted-In: Cowen & CoAnalyst Color Initiation Analyst Ratings


Related Articles (STJ + QURE)

View Comments and Join the Discussion!

Deutsche Bank Hits Energizer With Buy On 'Environment + ROC + M&A'

Top Performing Industries For July 15, 2015