American CareSource Holdings Increases Value to Providers, Clients, and Patients with Web Portal Release

After months of research, planning and development, American CareSource Holdings (NASDAQ: ANCI) today announced the phased launch of their three new educational and communications portals on the Ancillary Care Services (ACS) website at www.anci-care.com. Built in conjunction with HealthBanks, Inc., an innovative industry leader in internet-based patient communication and health education programs, and Collabrian, an international, award-winning software development and graphic design company specializing in the development of large-scale database-driven desktop and internet applications, the three new portals – Provider, Client, and Patient – will create a value-add service to ACS’ ancillary service providers, PPO, TPA, and payor clients, and the consumer like no other.

“These three portals are important components in our collective efforts to reduce the cost of healthcare spending in the US. Our clients and our providers are committed to providing lower cost alternatives to hospital and physician office-based services. Collectively, our ultimate objective is to make it possible for the consumer to become educated about their healthcare costs and take control of managing their healthcare service options,” said ACS President and CEO David Boone. “Each of these portals will make it possible for our clients, our network providers, and the patient consumer to work together to instigate change in the healthcare industry. We are very excited about the launch of these important educational portals, and view the launch as yet another opportunity for ACS to distinguish itself as an industry leader in the ancillary services segment of healthcare.”

“The phased rollout of the integrated ACS portals will begin with the Provider Portal launch on April 1, 2010, followed by the ACS Client Portal launch on May 1, 2010, and the public-facing Patient Portal on June 1, 2010,” said ACS Chief Information Officer Rost Ginevich. “This collaborative effort between the ACS Development Team, Collabrian and HealthBanks will add tremendous value to our Clients, Providers and Members by simplifying and accelerating many of the interactions between all parties.”

About HealthBanks

Since 1993 HealthBanks has provided leading patient education and e-marketing services to the healthcare sector. Its first products (pre-Internet) were interactive patient education kiosks which resided in physician offices and hospitals (including the Mayo Clinic). Today, HealthBanks generates measurable results for its customers through its award-winning patient education and e-marketing platform designed specifically for healthcare. HealthBanks, Inc. is a privately held company based in Burlington, Massachusetts.

About Collabrian Design & Technology

Collabrian is an award-winning, full-service software development company and systems integrator. Founded in 2000, the company focuses on the design and development of database-driven systems for both web and desktop for cross-industry clients including those in healthcare, mortgage, and education.

About American CareSource Holdings, Inc.

American CareSource Holdings, the first national, publicly traded ancillary care network services company, offers a comprehensive national network of over 4,100 ancillary service providers at more than 33,000 sites through its subsidiary, Ancillary Care Services. Ancillary Care Services provides ancillary health care services through its network that offers cost effective alternatives to physician and hospital-based services. This market is estimated at $574 billion and has grown to over 21% of total national health expenditures. These providers offer services in 31 categories including laboratories, dialysis centers, free-standing diagnostic imaging centers, non-hospital surgery centers, as well as durable medical equipment such as orthotics and prosthetics and others.

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Safe Harbor Statement Under the Private Securities Litigation Reform Act of 1995:

Any statements that are not historical facts contained in this release, including with respect to the Company's plans, objectives and expectations for future operations, projections of the Company's future operating results or financial condition, and expectations regarding the health care industry and economic conditions, are forward-looking statements. Substantial risks and uncertainties could cause actual results to differ materially from those indicated by forward-looking statements, including, but not limited to, changes in national health care policy, regulation, general economic conditions, demand for ancillary services, pricing, competition, market acceptance/preference, the Company's ability to integrate with its clients, changes in the business decisions by key clients or consolidation in the industry affecting them, the Company's inability to attract or maintain providers or clients or to manage growth, implementation and performance difficulties, and other risk factors detailed from time to time in the Company's periodic filings with the Securities and Exchange Commission. Except as otherwise required by law, the Company undertakes no obligation to update or revise these forward-looking statements.