Mid-Afternoon Market Update: Oncomed Pharmaceuticals Slides After Poor Trial Data; Sunedison Shares Rise

Toward the end of trading Monday, the Dow traded down 0.48 percent to 16,015.68 while the NASDAQ slipped 0.61 percent to 4,563.25. The S&P also fell, dropping 0.68 percent to 1,894.02.

On Monday, healthcare shares rose by 0.25 percent. Meanwhile, top gainers in the sector included

, up 15 percent, and

, up 8 percent. In trading on Monday, energy shares tumbled by 1.91 percent. Meanwhile, top losers in the sector included

, down 18 percent, and

, down 13 percent.

reported better-than-expected results for its fourth quarter on Monday. McDonald's posted quarterly net income of $1.21 billion, or $1.31 per share, compared to $1.1 billion, or $1.13 per share, in the year-ago period. Its sales rose to $6.34 billion from $6.57 billion. However, analysts were expecting earnings of $1.23 per share on revenue of $6.22 billion.

shares shot up 25 percent to $5.26 after the company reported a merger deal at $6 per share. Shares of

got a boost, shooting up 10 percent to $33.66.

entered into a definitive merger agreement with Tyco International.

shares were also up, gaining 5 percent to $2.78. According to the Wall Street Journal's report, David Einhorn's Greenlight Capital will be given a seat a Sunedison's board of directors.

shares dropped 43 percent to $10.02 after the company provided an update on its Phase 2 ALPINE clinical trial following a pre-planned January 23 interim efficacy assessment of the clinical trial by an independent data safety monitoring board. Shares of

were down 22 percent to $13.64. Macquarie downgraded KapStone Paper and Packaging from Neutral to Underperform.

was down, falling around 10 percent to $32.86. Citigroup downgraded International Paper from Buy to Neutral.

In commodity news, oil traded down 3.88 percent to $30.94, while gold traded up 0.79 percent to $1,105.00. Silver traded up 1.27 percent Monday to $14.24, while copper fell 0.37 percent to $2.00.

European shares closed lower today. The eurozone's STOXX 600 fell 0.62 percent, the Spanish Ibex Index dropped 1.78 percent, while Italy's FTSE MIB Index dipped 2.03 percent. Meanwhile, the German DAX declined 0.29 percent, and the French CAC 40 slipped 0.58 percent, while U.K. shares fell 0.39 percent.

The Dallas Fed manufacturing business index tumbled to -34.6 in January, versus a prior redaing of -20.10. However, economists were expecting a reading of -15.00.